Sökning: "blood group"
Visar resultat 1 - 5 av 1117 avhandlingar innehållade orden blood group.
1. Elucidating the Blood Group Regulome
Sammanfattning : .... LÄS MER
2. Molecular Genetic Studies of the Blood Group ABO Locus in Man
Sammanfattning : The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. LÄS MER
3. Identification and characterisation of SMIM1 variants determining the Vel blood group
Sammanfattning : The Vel blood group antigen is present on red blood cells from all humans except rare Vel-negative individuals, who can form antibodies to Vel in response to transfusion or pregnancy. It was first described in 1952 as a high incidence antigen, while the molecular background was recently discovered to be a 17-bp deletion in Small Integral Membrane Protein 1, that causes a frame-shift mutation and abolishes SMIM1 expression, thus creating a Vel-negative phenotype. LÄS MER
4. Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens
Sammanfattning : Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. LÄS MER
5. Human intestinal alkaline phosphatase : tissue expression and serum levels
Sammanfattning : Human alkaline phosphatase (ALP) comprises four isozymes, viz liver/bone/ kidney or tissue unspecific (AP), intestinal (LAP), placental (PLAP) and germ cell or PLAP-like alkaline phosphatase, with their main expression in specific tissues as indicated by their names. The isozymes are coded by different genes, but they are closely related, with more than 50% amino acid sequence homologies. LÄS MER