Sökning: "blood donor screening"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden blood donor screening.

  1. 1. GB virus C/hepatitis G virus infection: clinical, histological and epidemiological aspects

    Författare :Per Björkman; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopy; nosocomial; sexual transmission; parenteral transmission; blood donor; ALT; liver disease; hepatitis; GBV-C HGV; HCV; Infections; Infektioner;

    Sammanfattning : GBV-C/HGV is a blood-borne virus related to the hepatitis C virus. We studied GBV-C/HGV infection in different populations, its transmission, and its association with liver disease. GBV-C/HGV viraemia was detected by PCR in 19/576 blood donors. Donors with normal and elevated ALT levels had similar rates of viraemia (1. LÄS MER

  3. 2. Prevention of transfusion transmitted infections : donor screening and characteristics of recipient populations

    Författare :Elsa Tynell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HTLV-I and II; blood donor screening; transfusion recipients; case-mix; survival rates; false-reactive test results; cost effectiveness;

    Sammanfattning : Minimising the risk for transfusion transmitted infections (TTIs) relies on selection of safe donors, including microbiological screening, and avoidance of unnecessary transfusions. Blood donor screening for HTLV-I and II, was introduced in Sweden in 1994. LÄS MER

  4. 3. Blood donors' long-term health : implications for transfusion safety

    Författare :Gustaf Edgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epidemiology; hemovigilance; neoplasms; mortality; blood donors; blood transfusion; transfusion safety;

    Sammanfattning : Continuous attention to transfusion safety through improvement of disease screening and donor selection has succeeded in reducing the risks of transfusion transmitted disease to practically immeasurable levels. Despite this progress, surprisingly little is known about disease occurrence among blood donors and whether there are possible long-term effects of repeated whole-blood or apheresis donation. LÄS MER

  5. 4. Studies of Thai blood group and platelet polymorphism. Implications for malaria susceptibility

    Författare :Philaiphon Jongruamklang; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thai; Blood group polymorphism; Human platelet antigens; Malaria susceptibility; Plasmodium falciparum;

    Sammanfattning : The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. LÄS MER

  7. 5. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy

    Författare :Simon Hultmark; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acute myeloid leukaemia; Hematologi; stem cells; differentiation induction; leukaemia; treatment; small molecule drugs; PKC; FLT3; shRNA; small molecule inhibitor; Small Molecule Libraries; MEK ERK pathway; natural product; co-culture; drug screening; combination therapy;

    Sammanfattning : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. LÄS MER