Sökning: "bleomycin"
Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet bleomycin.
1. Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis
Sammanfattning : .... LÄS MER
2. Repair of DNA double-stranded breaks in human cells
Sammanfattning : DNA is continuously subjected to degradation. Therefore, our cells need to constantly repair its DNA to prevent mutations and in the long run cancer. In mammalian cells, when DNA is broken right off, a double-stranded break (DSB) is produced, and the ends are ligated by a process called non-homologous end-joining (NHEJ). LÄS MER
3. Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects
Sammanfattning : Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. LÄS MER
4. Molecular characterization of phenothiazines in experimental cancer therapy : new tricks of an old drug revealed
Sammanfattning : Cancer is characterized by uncontrolled malignant proliferation of cells that eventually interfere with tissue/organ functions. Traditionally, cancer is treated with chemo- and/or radiotherapy when surgery is not an option. Unfortunately, the efficacy of conventional anti-cancer chemotherapy is severely limited by therapy resistance. LÄS MER
5. Galectin Inhibitors – Molecular Tools in Biomedical Research and Clinical Implications
Sammanfattning : Galectins are β-galactoside-binding lectins, which are present in both the intracellular and extracellular environments of cells. During the last two decades, galectins have gained increasing interest as drug targets in various diseases, such as chronic inflammation (fibrosis) and cancer, in which galectins have been shown to play important, and sometimes rate-limiting, roles. LÄS MER
