Sökning: "bladder carcinoma"

Visar resultat 31 - 35 av 44 avhandlingar innehållade orden bladder carcinoma.

  1. 31. Fluorescence in situ hybridization for the detection of genetic alterations in prostate and bladder malignancies : significance as a genetic marker to predict the patient prognosis

    Författare :Hideyasu Matsuyama; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :prostate cancer bladder cancer tumor suppressor gene chromosomal deletion chromosome 8p; chromosome lOq chromosome 16q; fluorescence in situ hybridization Prostate cancer and bladder cancer are common urological malignancies in man; while a lack of;

    Sammanfattning : Prostate cancer and bladder cancer are common urological malignancies in man, while a lack of basic information underlying the oncogenesis and the tumor progression makes it difficult to form therapeutic strategies against these malignancies. Recent advances of molecular biology revealed that genetic alteration play a crucial role in the oncogenesis and progression of these tumors. LÄS MER

  3. 32. Nitric oxide : a marker for inflammation in the lower urinary tract

    Författare :Abolfazl Hosseini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The main aim of this work is to investigate the role of Nitric oxide (NO) as a diagnostic marker for inflammation in the lower urinary tract. NO exerts multiple modulating effects on inflammation and plays a key role in the regulation of immune responses. NO is formed enzymatically in vivo from Larginine by several NO synthases (NOS). LÄS MER

  4. 33. On the role of nitric oxide in lower urinary tract disease

    Författare :Lotta Renström Koskela; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nitric oxide (NO) is an important biological molecule with a variety of functions. Among other, it is a signalling molecule capable of inducing smooth muscle relaxation and vasodilatation, it regulates proliferation, can induce apoptosis and act as an effector molecule in host defence reactions and in immune regulatory processes. LÄS MER

  5. 34. Familial risks for cancer with reference to lung cancer

    Författare :Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

    Sammanfattning : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. LÄS MER

  7. 35. On the role of bioactive sphingolipids and their metabolizing enzymes in cancer

    Författare :Dilruba Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Ceramide is a family of closely related molecules, which are presumed to be in the center of sphingolipid metabolism. Among sphingolipid metabolites, several ceramide subspecies and sphingosine induce apoptosis, cell cycle arrest and death, whereas sphingosine 1-phosphate (S1P) mediates cell proliferation, invasion, angiogenesis and metastasis. LÄS MER