Sökning: "bipolar disorders"

Visar resultat 16 - 20 av 71 avhandlingar innehållade orden bipolar disorders.

  1. 16. Integration of functional genomics and data mining methodologies in the study of bipolar disorder and schizophrenia

    Författare :Marianthi Logotheti; Nikolaos Venizelos; Fragiskos Kolisis; Nikos Stefanis; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar Disorder; Schizophrenia; Fibroblasts; DNA Microarrays; Machine Learning; Functional Analysis; Gene Expression; Transcriptomics;

    Sammanfattning : Bipolar disorder and schizophrenia are two severe psychiatric disorders characterized by a complex genetic basis, coupled to the influence of environmental factors. In this thesis, functional genomic analysis tools were used for the study of the underlying pathophysiology of these disorders, focusing on gene expression and function on a global scale with the application of high-throughput methods. LÄS MER

  3. 17. Amino acid transport and receptor binding properties in neuropsychiatric disorders using the fibroblast cell model

    Författare :Jessica Johansson; Nikolaos Venizelos; Lars Oreland; Örebro universitet; []
    Nyckelord :Fibroblasts; Bipolar disorder; ADHD; Tyrosine; Tryptophan; Alanine; Transport; mAChRs; Biomedicin; Biomedicine;

    Sammanfattning : Altered transport of the catecholamines and serotonin precursor amino acids tyrosine and tryptophan, might be one explanation for the dysfunctional neurotransmission implicated in the pathophysiology of bipolar disorder and Attention Deficit/Hyperactivity Disorder (ADHD). In previous studies, an altered amino acid transport has been found in schizophrenia and autism, when using the fibroblast cell model. LÄS MER

  4. 18. Long-term Outcome, Suicidal behaviour, Quality of Life and Expressed Emotion in Adolescent Onset Psychotic Disorders

    Författare :Håkan Jarbin; Helmut Remschmidt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Child and adolescent psychiatry; schizophrenia; affective disorder; bipolar disorder; outcome; suicide; quality of life; expressed emotion; Barn- och ungdomspsykiatri; Child and adolescent psychiatry; Barn- och ungdomspsykiatri; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Sammanfattning : This study investigated a consecutive cohort of 88 youngsters with onset of a psychotic disorder at age 15.7 (sd 1.5) years and followed-up 10.6 (sd 3. LÄS MER

  5. 19. Psychotic disorders in the Lundby population 1947-1997: Incidence, life-time prevalence and predictors related to personality and behaviour

    Författare :Mats Bogren; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; psychotic disorder; prevalence; bipolar disorder; incidence; prospective study; methodology; community survey; the Lundby Study.; epidemiology;

    Sammanfattning : The aims were to analyze the first incidence, age-at-onset, prevalence and personality related predictors of psychotic disorders in the Lundby population (n=3563) – a community population followed through four waves of field study 1947-1997. Case ascertainment included interviews, registers, case notes and key informants. LÄS MER

  7. 20. Structural magnetic resonance imaging of bipolar disorder

    Författare :Carl Johan Ekman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bipolar disorders are illnesses with recurring episodes of elevated or depressed mood. Although most affected individuals have periods when they are free of symptoms, they carry a life-long risk of relapse. The cause of the illness has not yet been established. LÄS MER