Avancerad sökning

Hittade 3 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Cellular pathways and molecular regulation of hematopoietic stem cells

   Författare :Kristina Anderson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

   Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. LÄS MER

3. 2. Lineage commitment to a T

   Författare :Sidinh Luc; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic stem cell; hematopoiesis; lineage commitment; lymphoid-primed multipotent progenitor;

   Sammanfattning : he hematopoietic development is a highly dynamic but tightly regulated process. The flexibility to produce blood cells through more than one route will allow the blood system to respond rapidly in stress situations such as infections. LÄS MER

4. 3. Studies on myeloid differentiation: cytokine influence and identification of a novel marker gene

   Författare :Karin Dannaeus; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; MYADM; stem cell factor; Flt3 ligand; Hematopoiesis; Hematologi; extracellulära vätskor;

   Sammanfattning : Hematopoiesis is a highly complex process by which a range of specialized blood cells are generated from a small pool of multipotent stem cells in the bone marrow. The survival, proliferation, and differentiation of hematopoietic stem cells are tightly regulated by both soluble and membrane-bound cytokines produced within the bone marrow microenvironment. LÄS MER