Sökning: "biosensor"

Visar resultat 11 - 15 av 206 avhandlingar innehållade ordet biosensor.

  1. 11. Signaling for color change in melanophores : and a biosensor application

    Författare :Annika M. Karlsson; Samuel Svensson; Margareta Wallin; Linköpings universitet; []
    Nyckelord :color change; melanophores; tyrosine; phosphorylations; melatonin; nitric oxide; MEDICINE; MEDICIN;

    Sammanfattning : Melanophores are dark brown pigment cells located in the skin of fish, amphibia, reptiles, and many invertebrates. The color of the animal can change via rearrangement of pigment granules, melanosomes, in the cells. The dark melanophores can either hide colorful cells so that the animal appears dark, or let through colors from underneath. LÄS MER

  3. 12. Functional aspects of cellobiose dehydrogenase Applications for biosensor development

    Författare :Leonard Stoica; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Elektrokemi; Electrochemistry; Analytisk kemi; Analytical chemistry; bioelectrochemistry; direct electron transfer; lactose biosensor;

    Sammanfattning : Electrochemcial investigations were conducted for elucidating and understanding the relation between the various electron transfer processes occurring in cellobiose dehydrogenase (CDH) bound to an electrode surface. Substrate inhibition caused by cellobiose was proven to act in competition with the electron transfer to a two-electron acceptor and under a partial inhibition mechanism for the internal electron transfer process. LÄS MER

  4. 13. Biosensor Studies of Ligand Interactions with Structurally Flexible Enzymes : Applications for Antiviral Drug Development

    Författare :Matthis Geitmann; U. Helena Danielson; Marc H. V. van Regenmortel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; SPR biosensor; HIV-1 reverse transcriptase; HCMV protease; interaction kinetics; drug discovery; non-nucleoside inhibitor; resistance; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : The use of a surface plasmon biosensor fills a missing link in kinetic studies of enzymes, since it measures directly the interaction between biomolecules and allows determination of parameters that are determined only indirectly in activity assays. The present thesis deals with kinetic and dynamic aspects of ligand binding to two viral enzymes: the human cytomegalovirus (HCMV) protease and the human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT). LÄS MER

  5. 14. Enzyme-Based Amperometric Biosensors in Flow-Systems for Biomolecule Detection

    Författare :Niklas Larsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microdialysis; Liquid chromatography; Flow injection; Polyelectrolytes; Carbohydrate; Mediator; Dehydrogenase; Peroxidase; Oxidase; Enzyme; Amperometric detection; Carbon paste; Biosensor; Graphite electrode; On-line monitoring; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Amperometric enzyme based biosensors were designed, developed and characterised in flow systems. Solid graphite and carbon paste electrodes were used as support for enzyme immobilisation. Both mediated and direct electron transfers between redox enzymes and electrodes were utilised for biosensor construction, as well as coupled enzyme systems. LÄS MER

  7. 15. Design, Development and Applications of Highly Sensitive Protein-Based Capacitive Biosensors

    Författare :Ibolya Bontidean; Kemiska institutionen; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biotechnology; Contaminated soil; Heavy metals; Lac repressor; Phytochelatin; MerP; MerR; SmtA; Self-assembled monolayer; Biosensor; Capacitance;

    Sammanfattning : Highly sensitive biosensors were developed for environmental and medical applications. The biosensors were based on bioengineered proteins as biorecognition elements coupled to a highly sensitive capacitive transducer. LÄS MER