Sökning: "bioprocess design"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden bioprocess design.

1. 1. Bioprocess development for biochemical conversion of lignocellulose

   Författare :Ruifei Wang; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Lignocellulose; strain engineering; stress tolerance; kinetic modelling; high gravity; scale-up; biofuels; SSCF; process development; Saccharomyces cerevisiae;

   Sammanfattning : Due to its low environmental impact and high maturity of the fuel ethanol market, lignocellulosic ethanol is a promising option for reducing the carbon footprint in the transport sector. The characteristics of lignocellulosic feedstocks, such as varied sugar composition, low sugar density, low solubility, recalcitrance to enzymatic degradation, and inhibitors formed during thermochemical pretreatment, have so far limited the production process, and costs for conversion of lignocellulosic materials to ethanol are still high. LÄS MER

3. 2. Development of mathematical modelling for the glycosylation of IgG in CHO cell cultures

   Författare :Liang Zhang; Véronique Chotteau; Michael J. Betenbaugh; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chinese hamster ovary cells; glycosylation; IgG; mathematical modelling; experimental design; perfusion; carbon sources; GReBA; Bayesian network; probabilistic graphic model; Bioteknologi; Biotechnology;

   Sammanfattning : Chinese hamster ovary (CHO) cells are the most popular expression system for the production of biopharmaceuticals. More than 80% of the approved monoclonal antibodies (mAbs) or immunoglobulin G (IgG) are produced with these cells. Glycosylation is a usual post- translational modification important for therapeutic mAbs. LÄS MER

4. 3. Evaluation of Pretreatment and Process Configurations for Combined Ethanol and Biogas Production from Lignocellulosic Biomass

   Författare :Pia-Maria Bondesson; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Ethanol; biogas; lignocellulose; steam pretreatment; acid catalyst; acetic acid; phosphoric acid; sulphuric acid; xylose fermentation; co-fermentation; process design; SSCF;

   Sammanfattning : In view of global climate change and the increasing energy demand there is a need for renewable energy resources. This thesis discusses an energy-driven biorefinery concept based on the agricultural residues corn stover and wheat straw. The work is divided into two main parts. LÄS MER

5. 4. Process development for combined pentose and hexose fermentation

   Författare :Fredrik Nielsen; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioethanol; Lignocellulose; Xylose fermentation; Co-fermentation; Process design; Agricultural residues; Saccharomyces cerevisiae;

   Sammanfattning : Second-generation ethanol from lignocellulose is a sustainable alternative that can partially replace fossil fuels. To be competitive with first generation ethanol from sugar and starch crops and fossil fuels, the conversion efficiency and ethanol yields of second-generation ethanol conversion processes must be improved. LÄS MER

7. 5. Strain- and bioprocess-design strategies to increase production of (R)-3-hydroxybutyrate by Escherichia coli

   Författare :Mónica Guevara-Martínez; Gen Larsson; Antonius J. A. van Maris; Pau Ferrer; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; E. coli; R -3-hydroxybutyrate; metabolic engineering; bioprocess design; NADPH; acetic acid; thioesterase; BAC; Bioteknologi; Biotechnology;

   Sammanfattning : Microbial bio-based processes have emerged as an alternative to replace fossil-based processes for the production of fuels and chemicals. (R)-3-hydroxybutyrate (3HB) is a medium-value chemical that has gained special attention as a precursor of antibiotics and vitamins, as a monomer for the synthesis of tailor-made polyesters and as a nutritional source for eukaryotic cells. LÄS MER