Sökning: "biomolecular recognition"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden biomolecular recognition.

  1. 1. Biomolecular recognition : recombinant antibodies, phage display and eukaryotic cloning systems

    Författare :Michelle A. Alting-Mees; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Probing Biomolecular Recognition at the Single Molecule Level

    Författare :Anders Gunnarsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell membrane; TIRFM; liposome; time-of-flight secondary ion mass spectrometry; membrane receptor; single molecule; TOF-SIMS; molecular recognition; DNA; barcode; total internal reflection; multiplexing;

    Sammanfattning : Specific recognition between biomolecular partners contributes to a multitude of biochemical signaling within and between cells. The aim of this work has been to investigate the possibility to probe biomolecular recognition reactions at the smallest possible scale, the single molecule level. LÄS MER

  4. 3. Modelling biomolecular interactions

    Författare :Johan Bredenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Computational chemistry; molecular dynamics; nuclear receptors; force field parameterization; zinc fingers; DNA; proteins.;

    Sammanfattning : Computational approaches for understanding and aiding in molecular biology has increased in significance over the last decades, where a wealth of biochemical experiments have provided a solid ground for developing computer models that can be used to predict unresolved issues within biology. Molecular dynamics (MD) is one of these methods, based on classical laws, and suitable for handling large macromolecules in their natural environment, water. LÄS MER

  5. 4. Towards novel applications for biomolecular interactions at surfaces

    Författare :Pernilla Söderberg; Karl Hult; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular recognition; interactions; phage display; biomolecular interactions; phage; adenine; influenza virus replication; oseltamivir; imprinted polymers.;

    Sammanfattning : The focus of this thesis has been to examine two new concepts involving the interaction of biological agents with synthetic material surfaces.The feasibility of deploying phage display techniques for the screening of materials in non-biological media was examined in two studies. LÄS MER

  7. 5. Biomolecular Recognition Based on Field Induced Magnetic Bead Dynamics

    Författare :Rebecca Stjernberg Bejhed; Peter Svedlindh; Klas Gunnarsson; Maria Strömme; Teresa Zardán Gómez de la Torre; Christer Johansson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Magnetic biosensor; magnetic nanoparticle; DNA detection; Teknisk fysik; Engineering Science;

    Sammanfattning : In this thesis, three different read-out techniques for biomolecular recognition have been studied. All three techniques rely on the change in dynamic behaviour of probe functionalised magnetic beads after binding to a biomolecular target complementary to the probe. LÄS MER