Avancerad sökning

Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Proteome Profiling of Strawberry and Characterization of a Bet v 1-Homologous Allergen

   Författare :Rikard Alm; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biochemistry; Metabolism; Biokemi; Naturvetenskap; Plant biochemistry; Växtbiokemi; Respiratory system; Andningsorganen; Natural science; biomatematik; Bioinformatics; medical informatics; biomathematics biometrics; Bioinformatik; medicinsk informatik; speclust; proteios; biological variation; phenotypic plasticity; data management; DIGE; sequencing; isoform; allergen; Proteomics; strawberry;

   Sammanfattning : Strawberry (Fragaria ananassa) is an economically important crop, and recognised as an important source of antioxidants and bioactive compounds with health promoting effects. Yet increased incidence of allergy puts a limit to the choice of food for an increasing percentage of the population. LÄS MER

3. 2. Probalistic Methods In Genomic Data Analysis

   Författare :Thomas Breslin; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pathway profiling; Bioinformatics; medical informatics; biomathematics biometrics; Bioinformatik; medicinsk informatik; differential gene expression; probabilistic methods; Natural science; Naturvetenskap; biomatematik; annotation analysis; microarray; Fysicumarkivet A:2004:Breslin;

   Sammanfattning : In this thesis, three aspects of gene expression data analysis are discussed: Differential gene expression is addressed by a probabilistic method. Gene annotation enrichment analysis is discussed in the context of multiple hypothesis testing and the choice of null hypothesis. LÄS MER

4. 3. New methods for protein structure threading and domain identification

   Författare :Mats Lindstam; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biomatematik; Molecular biophysics; Molekylär biofysik; medicinsk informatik; Bioinformatik; biomathematics biometrics; medical informatics; structure prediction; Bioinformatics; domain identification; Structural bioinformatics; threading;

   Sammanfattning : The availability of three-dimensional structures of proteins has provided enormous insight into the detailed molecular machinery of the living cell. Since the late 1950s and early 1960s, experimental methods for deriving protein structures have contributed more than 30,000 entries to the Protein Data Bank, representing the collected knowledge of protein and other macromolecular structures. LÄS MER

5. 4. Statistical and Functional Analysis of Genomic and Proteomic Data

   Författare :Yingchun Liu; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; biomathematics biometrics; unsupervised classification; Bioinformatics; medical informatics; TGF-beta; linear mixed model; expression data; dye bias; 2D-gel; signaling pathway; regulatory motif; microarray; medicinsk informatik; biomatematik;

   Sammanfattning : High-throughput technologies have led to an explosion in the availability of data at the genome scale. Such data provide important information about cellular processes and causes of human diseases, as well as for drug discovery. Deciphering the biologically relevant results from these data requires comprehensive analytical methods. LÄS MER

7. 5. Insights into structure and dynamics of the AAA+ motor of magnesium chelatase

   Författare :Joakim Lundqvist; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; biomathematics biometrics; Bioinformatics; medical informatics; Rhodobacter capsulatus; Tetrapyrrole; Mutants; Magnesium chelatase; Cryo-Electron microscopy single-particle 3D reconstruction; Chlorophyll biosynthesis; AAA proteins; ATPase; medicinsk informatik; biomatematik; Molecular biophysics; Molekylär biofysik; Natural science; Naturvetenskap;

   Sammanfattning : The insertion of Mg2+ into protoporphyrin IX represents the first committed step in the chlorophyll and bacteriochlorophyll biosynthetic pathways. The reaction is catalyzed by the multisubunit enzyme Mg-chelatase, which consists of three subunits, known as I (molecular weight ~40 kDa), D (~70 kDa), and H (~140 kDa). LÄS MER