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Visar resultat 1 - 5 av 235 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Injectable Biomaterials for Spinal Applications

   Författare :Alejandro López; Cecilia Persson; Håkan Engqvist; Andreas Boger; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; injectable; biomaterials; bone cement; vertebral compression fractures; spine; radiopacity; minimally invasive treatment; low-modulus cement; oligomer; PMMA; calcium phosphate; vertebroplasty; bone; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

   Sammanfattning : The use of injectable biomaterials is growing as the demands for minimally invasive procedures, and more easily applicable implants become higher, but their availability is still limited due to the difficulties associated to their design.Each year, more than 700,000 vertebral compression fractures (VCF’s) are reported in the US and 500,000 VCF’s in Europe due to primary osteoporosis only. LÄS MER

3. 2. On the biological response to different biomaterials under normal and irradiated conditions

   Författare :Louise Rydén; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; bone; fibrosis; hydroxyapatite; inflammation; irradiation; Osseointegration; silicone; soft tissue; titanium;

   Sammanfattning : There are several challenges when introducing an implant into a host. Concerning soft tissues, major complications are fibrosis and capsule contracture, whereas for bone, failure of osseointegration may occur. LÄS MER

4. 3. Biomaterials and Hemocompatibility

   Författare :Anna E. Engberg; Kristina Nilsson Ekdahl; Peter Zipfel; Linnéuniversitetet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement; Coagulation; Whole blood; Biomaterials; Polymers and Hemocompatibility; Immunology; Immunologi; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Biomaterials are commonly used in the medical clinic today; however, artificial materials can activate the cascade systems in the blood (complement-, coagulation-, contact- and fibrinolytic systems) as well as the platelets to various degrees. When an artificial surface comes in contact with blood, plasma proteins will be adsorbed to the surface within seconds. LÄS MER

5. 4. Biomaterials as carriers for bone active molecules-An approach to create off-the-shelf bone substitutes

   Författare :Deepak Raina; Lund Ortopedi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; Bone tissue engineering; Bone morphogenic protein-2; Zoledronic acid ZA ; calcium sulphate; Hydroxyapatite; Gelatin;

   Sammanfattning : Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. LÄS MER

7. 5. Interactions between platelets and complement with implications for the regulation at surfaces

   Författare :Per H. Nilsson; Kristina Nilsson Ekdahl; John Lambris; Ian Nicholls; Berhane Ghebrehiwet; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system activation; regulation ; platelets activation; regulation ; biomaterials; biocompatibility; chondroitin sulfate-A; apyrase; C1q; C3; factor H; C4BP; ADP; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. LÄS MER