Sökning: "biomarker"

Visar resultat 11 - 15 av 777 avhandlingar innehållade ordet biomarker.

  1. 11. Integrative approaches in ecotoxicological testing: Implications for biomarker development and application

    Författare :Sara Furuhagen; Elena Gorokhova; Magnus Breitholtz; Lars Förlin; Ann-Kristin Eriksson Wiklund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biomarker; oxidative stress; Daphnia magna; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Ecotoxicology aims to understand toxic effects of chemicals in the environment. Effects can be observed at different levels of the biological organization, from molecular to ecosystem level. LÄS MER

  3. 12. From Proteomic Analysis to Biomarker Application - Studies of Carbonyl Reductase in Fish

    Författare :Eva Albertsson; Göteborgs universitet; []
    Nyckelord :Fish; Proteomics; Biomarker; Carbonyl Reductase; AhR agonists; Oxidative stress; Biomonitoring;

    Sammanfattning : Many anthropogenic substances are present in the aquatic environment, but there is limited information on how this combination of chemicals affects exposed wildlife. To assess the impact of chemicals, a biomarker approach is frequently applied in environmental biomonitoring programmes. LÄS MER

  4. 13. Chemical mixtures and interactions with detoxification mechanisms and biomarker responses in fish

    Författare :Johanna Gräns; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fish; AhR; CYP1A; PXR; Chemical mixtures; Chemical interaction; Biomarker;

    Sammanfattning : Several classes of anthropogenic chemicals are present as mixtures in the aquatic environment. However, information of how wildlife species, including fish, are affected by exposures to chemical mixtures is limited. LÄS MER

  5. 14. Molecular Characterisation and Prognostic Biomarker Discovery in Human Non-Small Cell Lung Cancer

    Författare :Karolina Edlund; Patrick Micke; Martin Schuler; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-small cell lung cancer; biomarker; prognosis; microarray; copy number aberration; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Non-small cell lung cancer (NSCLC) constitutes a clinically, histologically, and genetically heterogeneous disease entity that represents a major cause of cancer-related death. Early-stage patients, who undergo surgery with curative intent, experience high recurrence rates and the effect of adjuvant treatment is modest. LÄS MER

  7. 15. The postsynaptic protein neurogranin: a new item in the Alzheimer’s disease biomarker toolbox

    Författare :Hlin Kvartsberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CSF; brain tissue; Alzheimer s disease; biomarker; neurogranin;

    Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia affecting more than 50 million people worldwide today and is characterised by progressive cognitive decline. One of the earliest events in AD, which is also closely related to neuronal loss and the degree of dementia, is synaptic degeneration. LÄS MER