Sökning: "biomarker quantification"
Visar resultat 6 - 10 av 62 avhandlingar innehållade orden biomarker quantification.
6. Aggrecan fragments as biomarkers in osteoarthritis
Sammanfattning : Background: In osteoarthritis (OA) the balance of cartilage matrix synthesis and degradation is disturbed, resulting in a gradual destruction of the articular cartilage. Matrix components released into body fluids by proteolytic cleavage can be used as biomarkers of ongoing processes. LÄS MER
7. Proteomic profiling of bacterial host adaptation : Racing the Red Queen
Sammanfattning : Despite the discovery of antibiotics almost a century ago, infectious diseases continue to be a substantial cause of human mortality and morbidity worldwide, especially in developing countries. The adverse affects of infectious diseases are thought to increase over the coming years as the widespread misuse of antibiotic leads to the emergence of strains for which current therapies are ineffective. LÄS MER
8. Image Analysis Methods and Tools for Digital Histopathology Applications Relevant to Breast Cancer Diagnosis
Sammanfattning : In 2012, more than 1.6 million new cases of breast cancer were diagnosed and about half a million women died of breast cancer. The incidence has increased in the developing world. The mortality, however, has decreased. LÄS MER
9. Evaluation of amyloid precursor protein and ß-amyloid as biomarkers for Alzheimer s disease
Sammanfattning : Alzheimer s disease (AD) is a neurodegenerative disorder characterised by accumulations of neurofibrillary tangles and amyloid plaques. The major components of the amyloid deposits are the ß-amyloid (Aß) peptides derived from the amyloid precursor protein (APP). LÄS MER
10. A multivariate approach to computational molecular biology
Sammanfattning : This thesis describes the application of multivariate methods in analyses of genomic DNA sequences, gene expression and protein synthesis, which represent each of the steps in the central dogma of biology. The recent finalisation of large sequencing projects has given us a definable core of genetic data and large-scale methods for the dynamic quantification of gene expression and protein synthesis. LÄS MER