Sökning: "biomark- ers"

Hittade 2 avhandlingar innehållade orden biomark- ers.

1. 1. Antibody based plasma protein profiling

   Författare :Ulrika Qundos; Jochen M. Schwenk; Peter Nilsson; Mathias Uhlén; Ulrike Korf; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein profiling; plasma; antibody; affinity proteomics; biomark- ers; multiplex; assay development;

   Sammanfattning : This thesis is about protein profiling in serum and plasma using antibody suspension bead arrays for the analysis of biobanked samples and in the context of prostate cancer biomarker discovery. The influence of sample preparation methods on antibody based protein profiles were investigated (Papers I-III) and a prostate cancer candidate biomarker identified and verified (Papers III-V). LÄS MER

3. 2. Modeling environment effects on spectroscopic properties of biomarkers and catalytic mechanisms in enzymes

   Författare :Camilla Gustafsson; Patrick Norman; Daniel Escudero; KTH; []
   Nyckelord :Computational chemistry; spectroscopy; biocatalysis; water flow; biomarkers; Teoretisk kemi och biologi; Theoretical Chemistry and Biology;

   Sammanfattning : Arguably, humans are in need of both better diagnostic tools to prevent pro- gression of diseases as well as greener catalysts for synthesis of chemicals.Neurodegenerative diseases affecting neurons in the brain leads to demen- tias, where Alzheimer’s disease (AD) is the most prevalent. LÄS MER