Sökning: "biomarkör"
Visar resultat 16 - 20 av 36 avhandlingar innehållade ordet biomarkör.
16. The Temporomandibular Joint in Juvenile Idiopathic Arthritis : Psychosocial, clinical, imaging and parotid saliva biomarkers
Sammanfattning : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. The disease can affect the temporomandibular joint (TMJ) and cause orofacial growth disturbances, pain, and jaw dysfunction. TMJ arthritis is often asymptomatic and therefore a challenging joint to diagnose. LÄS MER
17. SOX11 as a Cancer Biomarker - Expression and Regulatory Studies in B-cell Lymphomas and Ovarian Cancer
Sammanfattning : It is estimated that one third of all people in Sweden will be diagnosed with cancer during their lifetime. The outcome for a specific patient is related to early and correct diagnosis, and prediction of effective treatment regimens. Biomarkers are molecules that can aid the clinician in such decisions regarding diagnosis, prognosis and therapy. LÄS MER
18. Maternal smoking during pregnancy - Long-term health effects in the offspring
Sammanfattning : Globally, around 10 % of women smoke during pregnancy today. It is known that pregnancy smoking increases the risk of adverse short-term health effects in the offspring, such as preterm birth, low birthweight and spontaneous abortion. Less is known about whether any adverse health effects persist until adulthood. LÄS MER
19. Identification, Validation and Implementation of Blastemal Biomarkers in Wilms Tumour
Sammanfattning : The aim of this thesis has been to establish biomarkers for the blastemal element in Wilms tumour (WT) – the most common paediatric kidney cancer. Blastema is, together with epithelium and stroma, one of the three common histological elements of WT. WTs dominated by blastema after preoperative chemotherapy are classified as high risk tumours. LÄS MER
20. Mechanisms of defective insulin secretion in type 2 diabetes
Sammanfattning : Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. LÄS MER