Sökning: "biological warfare"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden biological warfare.

  1. 1. Responsible Conduct in Dual Use Research : Towards an Ethic of Deliberation in the Life Sciences

    Författare :Frida Kuhlau; Anna T Höglund; Stefan Eriksson; Kathinka Evers; Alexander Kelle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bioethics; biological warfare; biological weapons; biosecurity; communicative ethics; deliberative ethics; dual use; ethical competence; life science research; precautionary principle; responsible conduct; Bioetik; Bioethics;

    Sammanfattning : Life scientists have increasingly been asked to incorporate a dual use responsibility in their research conduct. In this thesis, different aspects of what constitutes a reasonable responsibility in terms of avoiding harmful misuse of research for biological weapon purposes have been explored. LÄS MER

  3. 2. Too close for comfort : The role of Contact-Dependent growth Inhibition (CDI) in interbacterial competition and cooperation

    Författare :Marcus Wäneskog; Sanna Koskiniemi; Paul Rainey; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial interactions; cell-cell binding; contact-dependent growth inhibition; CDI; CdiB; CdiA; CdiI; outer-membrane receptor; BamA; OmpC; OmpF; extracellular toxin delivery; Toxin-Antitoxin; TA-system; persister cells; stress tolerance; stress response; rpoS; rssB; quorum sensing; multicellular behavior; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Contact-Dependent growth inhibition (CDI) was discovered in 2005 in the E. coli isolate EC93. Since then our knowledge of CDI systems and their impact on bacterial communities have increased exponentially. LÄS MER

  4. 3. Computational Modeling of the Mechanisms and Selectivity of Organophosphate Hydrolases

    Författare :Miha Purg; Shina C. Lynn Kamerlin; Iñaki Tuñón; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Organophosphate Hydrolase; Computational enzymology; MPH; DFPase; PON1; Empirical Valence Bond; EVB;

    Sammanfattning : Computational modeling is becoming an increasingly integral part of (bio)chemistry, providing a powerful complementary view into the dynamics, binding, and reactivity of biochemical systems. In particular, molecular simulations based on multiscale models are now regularly employed in studies of enzymatic reactions, offering invaluable mechanistic insight through the lens of molecular energy landscapes. LÄS MER

  5. 4. Nano- and Micro-sized Molecularly Imprinted Polymer Particles on Solid Surfaces

    Författare :Tripta Kamra; Synkrotronljusfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Molecularly imprinted polymers (MIPs) are artificial receptors made by imprinting template molecules in a polymer matrix followed by their removal through washing to obtain a specific and selective template cavities. This property of the MIPs have made them a very efficient material for diverse applications such as chromatography, purification, drug sensing, etc. LÄS MER

  7. 5. PCR and sequencing based methods for detection and typing of pathogenic microorganisms

    Författare :Tara Wahab; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The potential use of bacteria and viruses as biological terror weapons makes certain highly pathogenic microorganisms a worldwide public health threat. In an outbreak investigation involving a possible deliberate spread of a biological warfare agent there is a need for a fast and reliable diagnostic method. LÄS MER