Sökning: "biological cost of resistance"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden biological cost of resistance.

  1. 11. Causes and consequences of blood parasite infections in birds

    Författare :Martin Stjernman; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Animal physiology; Djurfysiologi; Parasitologi människa och djur ; Parasitology human and animal ; maternal transfer; stabilising selection; parasite resistance; parasites; trade-off; cost of reproduction; Ficedula hypoleuca; pied flycatcher; Haemoproteus; blue tit; Parus caeruleus;

    Sammanfattning : Parasites are ubiquitous and can cause significant fitness reductions to their hosts. Therefore, selection for the evolution of host resistance should be strong. However, resistance may be costly and should be traded-off against other fitness related traits. LÄS MER

  3. 12. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

    Författare :Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER

  4. 13. Defence and signalling in Potato-Phytophthora infestans interactions

    Författare :Ashfaq Ali; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phytophthora infestans; Plant defence; hypersensitive response; resistance; susceptibility;

    Sammanfattning : Potato is one of the major food crops and its yield is severely affected by late blight disease caused by Phytophthora infestans. P. infestans has the ability to manipulate plant defence signalling by secreting effector molecules causing so called effector triggered susceptibility. LÄS MER

  5. 14. Physiological trade-offs in reproduction and condition dependence of a secondary sexual trait

    Författare :Måns S. Andersson; Victor Apanius; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Trade-offs; life history; immune ecology; cost of reproduction; costs of immune response; sexual selection; migration; moult; Newcastle disease; HbA1C; Ficedula albicollis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Animal Ecology; zooekologi;

    Sammanfattning : This thesis examines parental condition, how it is traded off against reproduction and how it is displayed in a secondary sexual trait. The studies were performed on nest-box breeding collared flycatchers Ficedula albicollis on the island of Gotland, in the Baltic Sea. LÄS MER

  7. 15. Deradicalising Giardiasis Treatment

    Författare :Sascha Krakovka; Staffan Svärd; Jon Jerlström-Hultqvist; Norbert Müller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; encystation; antibiotic resistance; metronidazole; transcriptomics; proteomics; thymidine kinase;

    Sammanfattning : Giardia intestinalis is a unicellular parasite causing the disease giardiasis. This disease is mostly prevalent in low resource settings, mandating low-cost treatment options. LÄS MER