Sökning: "biological cost of resistance"
Visar resultat 1 - 5 av 29 avhandlingar innehållade orden biological cost of resistance.
1. Multi-Resistance Plasmids Fitness Costs, Dynamics and Evolution
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Antibiotic resistance is an escalating problem, not only due to less desirable treatment options and outcome, but also due to the economic burden to health care caused by resistant pathogens. Since the process of developing new antibiotics is slow, we need to carefully consider the usage of the antibiotics still available. LÄS MER
2. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. LÄS MER
3. The biological cost of resistance to antibiotics
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : The rate of development and stability of antibiotic resistance are determined by several factors including (i) the mutation rate, (ii) the fitness costs of resistance, and (iii) the ability of bacteria to genetically compensate for such costs.. This study has focused on the experimental measurement of these parameters in antibiotic-resistant S. LÄS MER
4. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. LÄS MER
5. Defence and signalling in Potato-Phytophthora infestans interactions
Detta är en avhandling från Department of Biology, Lund UniversitySammanfattning : Potato is one of the major food crops and its yield is severely affected by late blight disease caused by Phytophthora infestans. P. infestans has the ability to manipulate plant defence signalling by secreting effector molecules causing so called effector triggered susceptibility. LÄS MER
