Avancerad sökning

Visar resultat 1 - 5 av 69 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Functional Cyclic Carbonate Monomers and Polycarbonates : Synthesis and Biomaterials Applications

   Författare :Jonas Mindemark; Tim Bowden; Andrew Dove; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA condensation; gene delivery; ionomers; polyplexes; self-assembly; amphiphiles; biodegradable; biological applications of polymers; transfection; cyclic carbonate monomers; polycarbonates; semicrystalline polymers; click chemistry; triazoles; cycloaddition; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

   Sammanfattning : The present work describes a selection of strategies for the synthesis of functional aliphatic polycarbonates. Using an end-group functionalization strategy, a series of DNA-binding cationic poly(trimethylene carbonate)s was synthesized for application as vectors for non-viral gene delivery. LÄS MER

3. 2. Engineering of thermometric biosensors and characterisation of redox enzymes for improved performance of biosensors/biofuel cells

   Författare :Maria Yakovleva; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Flow injection analysis; thermometric calorimetric biosensor; enzyme thermistor; immobilised enzyme reactor; amperometric biosensor; enzymatic biofuel cell; bioanode; pyranose dehydrogenase; cellobiose dehydrogenase; direct electron transfer; mediated electron transfer; matrix-assisted laser desorption ionization; glycosite mapping;

   Sammanfattning : The present work is mainly focused on the development of enzyme-based bioanalytical devices, which can further be applied as analytical tools for industrial, medical and environmental applications. The first part of the work deals with the practical applications of thermometric biosensors for determination of various sugars (fructose and lactose) in a real samples. LÄS MER

4. 3. Development of Liquid-based Separation Techniques using Tailored Surfaces for Analysis of Biological Samples

   Författare :Emilia Hardenborg; Jonas Bergquist; Marit Andersson; Alejandro Cifuentes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aqueous humor; biological samples; capillary electrophoresis; coatings; drugs; liquid chromatography; molecular imprinted polymers; peptides; proteins; pseudoexfoliation; Analytical chemistry; Analytisk kemi;

   Sammanfattning : Development and improvement of analytical techniques are vital in analytical chemistry research. This thesis describes the development and use of tailored surfaces for bioanalytical applications. LÄS MER

5. 4. Synthetic Functionalities for Ion and Electron Conductive Polymers : Applications in Organic Electronics and Biological Interfaces

   Författare :Tobias Abrahamsson; Magnus Berggren; Daniel Simon; Mikhail Vagin; David Bliman; Roger Gabrielsson; David Mecerreyes; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : In the search for understanding and communicating with all biological systems, in humans, animals, plants, and even microorganisms, we find a common language of all communicating via electrons, ions and molecules. Since the discovery of organic electronics, the ability to bridge the gap and communicate be-tween modern technology and biology has emerged. LÄS MER

7. 5. Synthesis, Characterisation and Properties of Biomimetic Biodegradable Polymers

   Författare :Fredrik Nederberg; Tim Bowden; Nicola Tirelli; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; biodegradable polymers; biomimetic; phospholipid-like; phosphorylcholine; amphiphilic; ionomer; hemocompatible; non-adhesive; water uptake; reduced protein adsorption; protein delivery; Kemi; Chemistry; Kemi;

   Sammanfattning : The acceptance of blood contacting implants creating favorable conditions in vivo is decisively determined by their interaction with proteins that mediate inter cellular interactions with synthetic substrates. Adsorbed proteins can activate blood cascade systems like coagulation and complement that may result in serious blood clots, and/or immunological reactions. LÄS MER