Avancerad sökning

Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Transition Metal Hydrides : Biomimetic Studies and Catalytic Applications

    Författare :Jesper Ekström; Hans Adolfsson; Jonathan Williams; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transition metals; catalysis; bioinorganic chemistry; hydrides; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : In this thesis, studies of the nature of different transition metal-hydride complexes are described. The first part deals with the enantioswitchable behaviour of rhodium complexes derived from amino acids, applied in asymmetric transfer hydrogenation of ketones. LÄS MER

  3. 2. Mechanistic Studies of Dinuclear Metalloenzymes - A Model Approach

    Författare :Håkan Carlsson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; models; Enzymes; bioinorganic chemistry; dinuclear; urease; nickel; zinc triphosphoesterase; Oorganisk kemi; Inorganic chemistry;

    Sammanfattning : With the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. LÄS MER

  4. 3. Synthetic [FeFe] Hydrogenase Active Site Model Complexes

    Författare :Lennart Schwartz; Sascha Ott; Marcetta Y. Darensbourg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; hydrogenase mimic; proton reduction; bioinorganic chemistry; diiron hexacarbonyl complexes; artifical photosynthesis; hydrogen; Organic chemistry; Organisk kemi;

    Sammanfattning : [FeFe]-Hydrogenases (H2ases) are metalloenzymes that can catalyze the reversible reduction of protons to molecular hydrogen as part of the metabolism of certain cyanobacteria and green algae. Due to the low availability of the enzyme, synthetic complexes that mimic the natural active site in structure, function and activity are highly sought after. LÄS MER

  5. 4. Theoretical aspects of tetrapyrrole biochemistry

    Författare :Kasper Jensen; Beräkningskemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteiner; enzymologi; Theoretical chemistry; quantum chemistry; Teoretisk kemi; kvantkemi; enzymology; Proteins; protein; enzyme; density functional; Heme; B12;

    Sammanfattning : Modern theoretical simulations are able to provide significant insight into biochemical problems on a scale which continues to expand. With the aid of computer power and the sophisticated programs of researchers in the field, we have addressed a series of problems related to the so-called tetrapyrrole cofactors found in all living organisms. LÄS MER

  7. 5. BIOACTIVE ORGANOMETALLIC COMPOUNDS

    Författare :Haris Bjelosevic; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological; kinetic; gold; platinum; bioactive; phosphine; ruthenocene; Ferrocene;

    Sammanfattning : Various metal complexes have been used in medicine traditionally, although their use was often connected with mystery and with a lack of empirically (clinically) proven effect. In modern times, the development of biochemistry, bioinorganic and bioorganometallic chemistry allows us more in-depth understanding of biological action of metal containing substances. LÄS MER