Sökning: "bioinformatics"
Visar resultat 11 - 15 av 632 avhandlingar innehållade ordet bioinformatics.
11. Formalizing life : Towards an improved understanding of the sequence-structure relationship in alpha-helical transmembrane proteins
Sammanfattning : Genes coding for alpha-helical transmembrane proteins constitute roughly 25% of the total number of genes in a typical organism. As these proteins are vital parts of many biological processes, an improved understanding of them is important for achieving a better understanding of the mechanisms that constitute life. LÄS MER
12. Bioinformatic Methods in Metagenomics
Sammanfattning : Microbial organisms are a vital part of our global ecosystem. Yet, our knowledge of them is still lacking. Direct sequencing of microbial communities, i.e. LÄS MER
13. Rule-based Models of Transcriptional Regulation and Complex Diseases : Applications and Development
Sammanfattning : As we gain increased understanding of genetic disorders and gene regulation more focus has turned towards complex interactions. Combinations of genes or gene and environmental factors have been suggested to explain the missing heritability behind complex diseases. LÄS MER
14. Computational methods for analysis of fragmented sequence data
Sammanfattning : Recent developments in genomic and proteomic sequencing technologies have revolutionized research in life sciences, providing new opportunities for the study of biological systems. However, modern sequence data sets are large, diverse, and heavily fragmented, which presents new challenges for their analysis and interpretation. LÄS MER
15. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows
Sammanfattning : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. LÄS MER