Sökning: "bioinformatics for proteomics"
Visar resultat 1 - 5 av 71 avhandlingar innehållade orden bioinformatics for proteomics.
1. Grid and High-Performance Computing for Applied Bioinformatics
Sammanfattning : The beginning of the twenty-first century has been characterized by an explosion of biological information. The avalanche of data grows daily and arises as a consequence of advances in the fields of molecular biology and genomics and proteomics. LÄS MER
2. Computational methods for analysis of fragmented sequence data
Sammanfattning : Recent developments in genomic and proteomic sequencing technologies have revolutionized research in life sciences, providing new opportunities for the study of biological systems. However, modern sequence data sets are large, diverse, and heavily fragmented, which presents new challenges for their analysis and interpretation. LÄS MER
3. Machine Learning methods in shotgun proteomics
Sammanfattning : As high-throughput biology experiments generate increasing amounts of data, the field is naturally turning to data-driven methods for the analysis and extraction of novel insights. These insights into biological systems are crucial for understanding disease progression, drug targets, treatment development, and diagnostics methods, ultimately leading to improving human health and well-being, as well as, deeper insight into cellular biology. LÄS MER
4. A multivariate approach to computational molecular biology
Sammanfattning : This thesis describes the application of multivariate methods in analyses of genomic DNA sequences, gene expression and protein synthesis, which represent each of the steps in the central dogma of biology. The recent finalisation of large sequencing projects has given us a definable core of genetic data and large-scale methods for the dynamic quantification of gene expression and protein synthesis. LÄS MER
5. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows
Sammanfattning : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. LÄS MER