Sökning: "biofysik"
Visar resultat 16 - 20 av 683 avhandlingar innehållade ordet biofysik.
16. From Static Structures to Free Energy Landscapes: Characterizing Conformational Transitions in Biological Macromolecules
Sammanfattning : To be alive means to temporarily counteract the fundamental dispersive driving force described by the second law of thermodynamics, eventually leading all systems to decay and disorder. In cells, this task is partly carried out by proteins - small specialized molecular machines that utilize free energy to maintain the proper functioning of the cell. LÄS MER
17. 3D super-resolution microscopy of living cells using reversibly switchable fluorophores
Sammanfattning : Traditional optical microscopy techniques are limited in spatial resolution due to the wave nature of light. This means that neighboring objects separated by a distance smaller than about 200 nm cannot be distinguished. LÄS MER
18. Automated super-resolution microscopy for high-throughput imaging
Sammanfattning : Fluorescence microscopes enable the visualization of biological samples with high contrast by labeling specific structures with fluorescent molecules. However, the spatial resolution of widely used microscopy techniques, such as widefield and confocal microscopy, is limited by the size of a focused spot of light, which roughly corresponds to half the wavelength of the illumination. LÄS MER
19. Investigation of Neuronal Protein Trafficking at the Molecular Scale
Sammanfattning : Neurons are polarized cells that encode information in the nervous system viaelectrochemical connections named synapses. The tuning of synapticconnections is enabled by a plastic protein trafficking system which operates atthe nanoscale to finely tweak the neuronal ultrastructure. LÄS MER
20. Advancing tissue clearing and expansion methods for high-resolution volumetric imaging of biological samples
Sammanfattning : The development of advanced light microscopes, capable of imaging samples at ever-higher spatial resolution and increasing speeds is an ongoing endeavour. The sample itself is an integral part of the microscope and, unlike the intricately positioned and highly polished lenses, it is an optically unpredictable component. LÄS MER