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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Development of highly biocompatible neuro-electronic interfaces towards monitoring authentic neuronal signaling in the brain

    Författare :Johan Agorelius; NanoLund: Centre for Nanoscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; BMI; brain machine interface; Neuro-electronic interface; neurophysiology; brain computer interface; biocompatibility; biocompatible neural interface; neural interface; histology; electrophysiology;

    Sammanfattning : Background: To understand how the neuronal circuits in the brain process information there is a need for novelneuro-electronic interfaces that can interact chronically with brain tissue with minimal disturbance of thephysiological conditions in the tissue, in awake and freely moving animals. For this, there is a need for implantableneuro-electronic interfaces that are mechanically compliant with the tissue and that can remain positionally stablewith respect to the neurons, despite the continuous micromotions in the brain. LÄS MER

  2. 2. Merging electronics and the brain - towards a fully biocompatible neural interface

    Författare :Gustav Lind; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural interface; neural implants; BMI; tissue reactions; biocompatibility; rat; astrocytes; microglia;

    Sammanfattning : Techniques for interfacing the nervous system using chronically implanted electrodes are turning into invaluable tools for neurophysiological research and treatment of neurological disorders. These methods have been developed and refined over the last decades. LÄS MER

  3. 3. A tailored biocompatible neural interface for long term monitoring in neural networks

    Författare :Per Köhler; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain-machine interfaces; neuroinflammation; somatosensory cortex; hyperalgesia; allodynia;

    Sammanfattning : Neural interface electrodes that can record from neurons in the brain for long periods of time will be of great importance to unravel how the brain accomplishes its functions. However, current electrodes usually cause significant glia reactions and loss of neurons within the adjacent brain parenchyma. LÄS MER

  4. 4. Microelectrode cluster technology for precise interactions with neuronal circuits. Towards highly specific adaptive deep brain stimulation

    Författare :Mohsin Mohammed; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neuro-electronic interfaceneural interface; neural interface; tissue reactions; deep brain stimulation; Adaptive DBS; biocompatibility; implantation method; neurosurgical tool;

    Sammanfattning : Neuro-electronic interfaces, which can be used for stable communication between neurons-computers over long periods of time, would be valuable for understanding and interacting with the nervous system. A major challenge has been to overcome the tissue reactions towards implanted electrodes. LÄS MER

  5. 5. A novel implantable ultra-flexible brain machine interface. Manufacturing and initial characterisations

    Författare :Fotios Tsanakalis; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain-Machine Interfaces; BMIs; Neural Interfaces; Electrodes;

    Sammanfattning : This thesis describes for the very first time the development of a miniaturized neural interface which is flexible in three dimensions (3D) to enable it to follow the brain movements with minimal dislocation. Both the design rationale and the material choice for the electrodes aim to develop interfaces that minimize the damage and/or the irritation of the tissue during and after the implantation. LÄS MER