Sökning: "biocompatibility"

Visar resultat 11 - 15 av 156 avhandlingar innehållade ordet biocompatibility.

  1. 11. Silicon nitride based coatings for biomedical implants

    Författare :Charlotte Skjöldebrand; Cecilia Persson; Håkan Engqvist; Julia Shelton; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; silicon nitride; ceramic coating; deposition; PVD; dissolution; biocompatibility;

    Sammanfattning : Silicon nitride-based coatings have been proposed as a means to reduce the release of metal ions and debris from metallic implants. This reduction in combination with the biocompatible debris from silicon nitride could result in a less adverse immune response. LÄS MER

  3. 12. Monocytes, Tissue Factor and Heparin-coated Surfaces : Clinical and Experimental Studies

    Författare :Matilda Johnell; Agneta Siegbahn; Rolf Larsson; Jesper Swedenborg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; monocytes; tissue factor; heparin-coated surfaces; coagulation; inflammation; thrombin; cytokines; cardiopulmonary bypass; biocompatibility; migration; chemotaxis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Cardiopulmonary bypass (CPB) is associated with inflammatory response and activation of coagulation. Heparin coating of the CPB circuit is shown to improve the biocompatibility of the surface. The biological effects of a new heparin surface, the Corline Heparin Surface (CHS), prepared according to a new principle, have been studied. LÄS MER

  4. 13. Toxicological and Immunomodulatory Properties of Mesoporous Silica Particles : Applications in Life Sciences

    Författare :Natalia Kupferschmidt; Alfonso E Garcia-Bennett; Susanne Gabrielsson; Mika Lindén; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mesoporous silica; biocompatibility; adjuvants; drug delivery systems; obesity;

    Sammanfattning : Mesoporous silica particles offer great potential benefits as vehicles for drug delivery and in other biomedical applications. They present a high loading capacity due their ordered and size-tuneable pores that allow molecules to be loaded and released. LÄS MER

  5. 14. Interactions between platelets and complement with implications for the regulation at surfaces

    Författare :Per H. Nilsson; Kristina Nilsson Ekdahl; John Lambris; Ian Nicholls; Berhane Ghebrehiwet; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system activation; regulation ; platelets activation; regulation ; biomaterials; biocompatibility; chondroitin sulfate-A; apyrase; C1q; C3; factor H; C4BP; ADP; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. LÄS MER

  7. 15. Silicon neural interfaces -Design and biomedical aspects-

    Författare :Lars Wallman; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Elektronik och elektroteknik; Electronics and Electrical technology; pn-etch stop; biocompatibility; neural recordings; porous silicon; silicon; neural interface; sieve electrode; General biomedical sciences; Biomedicinska vetenskaper allmänt ;

    Sammanfattning : This thesis covers the development of a silicon neural interface, with focus on silicon sieve electrode fabrication, design, nerve regeneration, signal recording and biocompatibility. A study of how the via hole size and transparency of the perforated sieve membrane influences the nerve regeneration is presented together with a study on soft tissue responses to planar and porous silicon. LÄS MER