Sökning: "biobanking"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet biobanking.

  1. 1. Breast cancer : Multifocality, heterogeneity, and related genetic signatures

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Gyula Pekar; Dumanski Jan; Sapino Anna; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast; breast cancer multifocality; molecular phenotypes; intertumoral heterogeneity; biobanking; gene copy number aberrations;

    Sammanfattning : Breast carcinoma often exhibits a complex subgross morphology and may occupy a large volume of the breast tissue and show unifocal, multifocal or diffuse growth patterns. Expression of estrogen- and progesterone receptors, HER2 overexpression, tumor grade, and proliferative activity allows us to classify breast carcinoma into molecular subgroups (Luminal A, Luminal B, HER2-type, triple negative, and basal-like). LÄS MER

  2. 2. Bioinformatic methods for metagenomics and comparative genetics in veterinary medicine

    Detta är en avhandling från ; Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences

    Författare :Martin Norling; Sveriges lantbruksuniversitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Good science includes innovation, investigation, and rigor. This thesis’ first study is related to rigor. This study was performed at the International Livestock Research Institute (ILRI) in Nairobi, as part of the Arbovirus Incidence and Diversity (AVID) project. LÄS MER

  3. 3. Trust in Biobank Research Meaning and Moral Significance

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Linus Johnsson; Mats G. Hansson; Gert Helgesson; Stefan Eriksson; Berge Solberg; [2013]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biobank; biobank research; bioethics; biobank ethics; research ethics; trust; trustworthiness; moral responsibility; informed consent; ethics review; ethics guidelines; Bioetik; Bioethics;

    Sammanfattning : What role should trust have in biobank research? Is it a scarce resource to be cultivated, or does its moral significance lie elsewhere? How does it relate to the researcher’s individual responsibility?In this thesis I draw four general conclusions. First, trust is still very much present in at least some biobanking settings, notably in Sweden, but possibly also internationally. LÄS MER

  4. 4. Depression : genetic, epigenetic and DNA biobank studies

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery

    Författare :Philippe A. Melas; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Depression is a disease that has an estimated lifetime prevalence of ~15% and a heritability of ~36%. There is support for a heterogeneous etiology of depression, which includes a) numerous genetic loci, b) various epigenetic contributors, and c) different environmental risk factors. LÄS MER

  5. 5. Establishment and applications of a multiple sclerosis biobank : Analysis of biomarkers and therapeutic complications in MS

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Författare :Ellen Iacobaeus; Karolinska Institutet.; Karolinska Institutet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Biomarkers for disease activity and prognosis in multiple sclerosis (MS) are lacking. We established a MS biobank consisting of paired cerebrospinal fluid samples (CSF) and peripheral blood samples from MS patients and controls. LÄS MER