Sökning: "biobank"

Visar resultat 1 - 5 av 69 avhandlingar innehållade ordet biobank.

1. 1. Biobank Research : Individual Rights and Public Benefit

   Författare :Joanna Stjernschantz Forsberg; Stefan Eriksson; Mats G. Hansson; Angus Dawson; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biobank; Ethics; Consent; Returning results; Individual rights; Public good; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis is to investigate the relationship between individuals and society in the context of healthcare and medical research, more specifically concerning the rights and duties of individuals in regard to biobank-based research. My starting point is that we all have a strong vested interest in improved healthcare, and therefore the possibilities to conduct important research should be optimized. LÄS MER

3. 2. Trust in Biobank Research : Meaning and Moral Significance

   Författare :Linus Johnsson; Mats G. Hansson; Gert Helgesson; Stefan Eriksson; Berge Solberg; Uppsala universitet; []
   Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biobank; biobank research; bioethics; biobank ethics; research ethics; trust; trustworthiness; moral responsibility; informed consent; ethics review; ethics guidelines; Bioetik; Bioethics;

   Sammanfattning : What role should trust have in biobank research? Is it a scarce resource to be cultivated, or does its moral significance lie elsewhere? How does it relate to the researcher’s individual responsibility?In this thesis I draw four general conclusions. First, trust is still very much present in at least some biobanking settings, notably in Sweden, but possibly also internationally. LÄS MER

4. 3. Usefulness of archival biobank samples for genetic epidemiologic studies

   Författare :Malin Sjöholm; Malmö Klinisk mikrobiologi; []
   Nyckelord :formailn-fixed paraffin-embedded tissue; biobank; serum; dried blood spots; plasma; archival samples;

   Sammanfattning : Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. LÄS MER

5. 4. Modeling glioblastoma heterogeneity to decipher its biology

   Författare :Yuan Xie; Lene Uhrbom; Massimo Squatrito; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Glioblastoma multiforme; biobank; GBM cells; cell of origin; LGR5; OPCs;

   Sammanfattning : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. LÄS MER

7. 5. Polyomavirus infections in humans

   Författare :Annika Lundstig; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Polyomaviruses; tumour virology; BK virus; neuroblastoma; maternal infection; Real Time PCR; enzyme immunoassay; seroprevalence; JC virus; SV40; virus like particles VLPs ; seroepidemiology; biobank; mesothelioma tissues; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : The human polyomaviruses BKV and JCV are endemic and infect > 70% of population worldwide. Primary infections occur during childhood and are largely subclinical. Following primary infection, both viruses persist as latent infections in the kidneys and B lymphocytes. LÄS MER