Sökning: "bioactive"

Visar resultat 1 - 5 av 268 avhandlingar innehållade ordet bioactive.

  1. 1. BIOACTIVE ORGANOMETALLIC COMPOUNDS

    Författare :Haris Bjelosevic; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological; kinetic; gold; platinum; bioactive; phosphine; ruthenocene; Ferrocene;

    Sammanfattning : Various metal complexes have been used in medicine traditionally, although their use was often connected with mystery and with a lack of empirically (clinically) proven effect. In modern times, the development of biochemistry, bioinorganic and bioorganometallic chemistry allows us more in-depth understanding of biological action of metal containing substances. LÄS MER

  3. 2. Expanded knowledge on silk assembly for development of bioactive silk coatings

    Författare :Linnea Nilebäck; My Hedhammar; Renko de Vries; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Recombinant spider silk; Self-assembly; Biomaterial; Implant coating; Functionalization; Multi-functional; Bioactive; Cell culture scaffold; Antibacterial; Bioteknologi; Biotechnology;

    Sammanfattning : Silk is a fascinating natural material made from proteins that self-assemble through structural rearrangements into one of the toughest materials known. As silk is protein-based, durable and elastic, it has many features that makes it suitable as a scaffold material for tissue engineering. LÄS MER

  4. 3. Understanding Composition–Structure–Bioactivity Correlations in Bioactive Glasses

    Författare :Yang Yu; Mattias Edén; Laurent Delevoye; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioactive glasses; Phosphosilicate glasses; Borophosphosilicate glasses; Solid-state NMR spectroscopy; Glass structure; Fourier-transform infrared spectroscopy; Hydroxyapatite; Amorphous calcium phosphate; Apatite formation; In vitro bioactivity testing; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Bioactive glasses integrate with bone/tooth tissues by forming a layer of hydroxy-carbonate apatite (HCA), which mimics the composition of bone mineral. In the current thesis, we investigated composition–structure–bioactivity correlations of phosphosilicate and borophosphosilicate (BPS) glasses. LÄS MER

  5. 4. Bioactive Lipids in Nociception

    Författare :Anna Ermund; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :Cannabinoids; Anandamide; AM404; 2-Arachidonoylglycerol; Acetaminophen; Cyclooxygenase; Nocicieption; TRPV1;

    Sammanfattning : This thesis focuses on bioactive lipids as (1) metabolites of the widely used antipyretic and analgesic drug acetaminophen and (2) activators of the ion channel TRPV1, an important downstream target for inflammatory mediators, in the phospholipase C (PLC)/TRPV1 signaling pathway. Evidence is presented for a fatty acid amide hydrolase (FAAH)-dependent fatty acid conjugation of p-aminophenol, a known acetaminophen metabolite, to form the potent TRPV1 activator AM404 in the central nervous system. LÄS MER

  7. 5. Exploring medical applications of a bioactive polymer

    Författare :Felix Sellberg; David Berglund; Buddy Ratner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bioactive polymer; oncology; immunology; radiology; ischemia; translational research;

    Sammanfattning : In this thesis, we have studied a polymeric compound called PVAC, designed as a scavenger of reactive electrophilic substances. We explored several diseases where these substances are overproduced.In Paper I, adhesion formation was induced via bowel anastomosis surgery in rats. LÄS MER