Sökning: "bioactive polymer"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden bioactive polymer.

  1. 1. Exploring medical applications of a bioactive polymer

    Författare :Felix Sellberg; David Berglund; Buddy Ratner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bioactive polymer; oncology; immunology; radiology; ischemia; translational research;

    Sammanfattning : In this thesis, we have studied a polymeric compound called PVAC, designed as a scavenger of reactive electrophilic substances. We explored several diseases where these substances are overproduced.In Paper I, adhesion formation was induced via bowel anastomosis surgery in rats. LÄS MER

  3. 2. Covalent Vapor-Phase Grafting of Degradable Polymers

    Författare :Martina Källrot; Ann-Christine Albertsson; Maria Nowokowska; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vapor-phase grafting; covalent surface modification; functionalization; solvent-free grafting; sub-micron patterned topography; scaffolds; degradable polymers; poly L-lactide ; poly ε-caprolactone ; poly trimethylene carbonate ; poly L-lactide-co-glycolide ; poly 1; 5-dioxepan-2-one-co-L-lactide ; poly ε-caprolactone-co-L-lactide ; N-vinylpyrrolidone; maleic anhydride; acrylamide; acrylic acid; hyaluronic acid; in vitro degradation; Gasfasympning; kovalent ytmodifiering; funktionalisering; lösningsmedelsfri ympning; sub-micrometer mönstrad topografi; nedbrytbara polymerer; poly L-laktid ; poly ε-kaprolakton ; poly trimetylen karbonat ; poly L-laktid-co-glykolid ; poly 1; 5-dioxepan-2-one-co-L-laktid ; poly ε-kaprolakton-co-L-laktid N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; akrylsyra; hyaluronsyra; in vitro nedbrytning; Polymer chemistry; Polymerkemi;

    Sammanfattning : Gasfasympning är en del i den moderna strategin för optimering av den molekylära designen av biomaterial. Kovalent ytmodifiering med hydrofila vinylmonomerer och koppling med bioaktiva grupper används för att öka biokompatibiliteten och bioaktiviteten hos biomaterialen.. LÄS MER

  4. 3. Functional Degradable Polymers by a Radical Chemistry approach

    Författare :Jenny Undin; Ann-Christine Albertsson; Anna Finne-Wistrand; Jukka Seppälä; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : One class of polymers that is inherently of great value for many applications is the aliphatic polyesters. Such polymers are very suitable for use as temporary guides, scaffolds, for tissue formation and other biomedical applications, due to their biocompatibility, degradability and appropriate mechanical properties. LÄS MER

  5. 4. Biomaterials for Promoting Self-Healing of Bone Tissue

    Författare :Sonya Piskounova; Jöns Hilborn; Tim Bowden; Simon Cool; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Osseointegration; implant coating; hyaluronan hydrogel; bone morphogenetic protein-2; hydroxyapatite; bone; delivery system; injectable; mixing; radioactive labeling; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Sammanfattning : The present work addresses poor bone/implant integration and severe bone defects. In both conditions external stimuli is required for new bone to form. LÄS MER

  7. 5. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis

    Författare :Sujit Kootala; Jöns Hilborn; Peter Thomsen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Osteoporosis; Bone regeneration; Biomaterials; Hyaluronic acid; Bisphosphonates; Osteoclasts; Osteoblasts; Growth factors; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Sammanfattning : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. LÄS MER