Sökning: "bicyclo[2.2.1]heptane"

Hittade 3 avhandlingar innehållade ordet bicyclo[2.2.1]heptane.

  1. 1. Synthesis of amino- and hydroxyl-substituted bridged bicyclic compounds and their application in asymmetric catalysis

    Författare :Cecilia Olsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; organocatalysis; asymmetric catalysis; bicyclo[2.2.1]heptane; bicyclo[2.2.2]octane; dibenzobicyclo[3.3.1]nonane; bioreduction; enzymatic kinetic resolution;

    Sammanfattning : In this work, hydroxyl- and amino-substituted bridged bicyclic compounds based on bicyclo[2.2.1]heptane, bicyclo[2.2. LÄS MER

  3. 2. Novel Pentofuranose Chemistry to Modulate RNA Function

    Författare :Mansoureh Karimiahmadabadi; Jyoti Chattapadhyaya; Jesper Wengel; Uppsala universitet; []
    Nyckelord :pentofuranose chemistry; conformationally locked nucleoside; carbocyclic-LNA; bicyclo[2.2.1]heptane;

    Sammanfattning : Chemical modifications of oligonucleotides provide an important tool to understand how the natural substrate works as well as how to improve their biochemical and biological properties as potential therapeutics and diagnostics. Our carba-LNA (2',4'-carba-bridged Locked Nucleic Acid) modified oligo-DNA or -RNA have been found to be useful to modulate oligo-RNA and -DNA activity. LÄS MER

  4. 3. Development of New Chiral Bicyclic Ligands : Applications in Catalytic Asymmetric Transfer Hydrogenation, Epoxidations, and Epoxide Rearrangements

    Författare :Arnaud Gayet; Andersson Pher G.; Hilmersson Göran; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; asymmetric catalysis; transfer hydrogenation; epoxide rearrangement; Organocatalysed epoxidation; chiral ligand; allylic alcohol; kinetic resolution; lithium amide; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes the synthesis and application of new chiral bicyclic ligands and their application in asymmetric catalysis. The studies involved: [i] The development of novel chiral bicyclic amino sulfur ligands and their use in transfer hydrogenation. LÄS MER