Sökning: "bicelles"

Visar resultat 6 - 10 av 15 avhandlingar innehållade ordet bicelles.

  1. 6. Development of Surface-Based Methods for Studies of Non-Electrolyte Membrane Transport

    Författare :Seyed Tabaei; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane junction; surface plasmon resonance; membrane transfer; supported lipid bilayer; quartz crystal microbalance; aquaporin; bicelles; fluorescence microscopy;

    Sammanfattning : Membrane-transport proteins are a diverse family of proteins that all span the cell membrane where they control the transfer of nutrients, metabolites and ions into and out of the cell. Due to their vital role for the function of cells, reliable methods, preferably with high-throughput capacity, to study this class of proteins are essential in fundamental studies as well as in discovery and development of new drugs. LÄS MER

  3. 7. The Application of isotropic bicelles as model membranes

    Författare :August Andersson; Lena Mäler; G Arthur III Palmer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bicelle; membrane; peptide; spectroscopy; NMR; Molecular biophysics; Molekylär biofysik;

    Sammanfattning : Isotropic bicelles are disc-shaped aggregates of lipids and detergents, and are suitable model systems for high-resolution NMR studies of membrane-interacting peptides. In this thesis the structures for the two peptides motilin and transportan were determined by homonuclear 1H methods in the presence of bicelles, and the structure of the bovine prion protein peptide (bPrPp) was solved in the presence of DHPC micelles. LÄS MER

  4. 8. Taming the Griffin : Membrane interactions of peripheral and monotopic glycosyltransferases and dynamics of bacterial and plant lipids in bicelles

    Författare :Jobst Liebau; Lena Mäler; Charles Sanders; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane; bicelle; lipid; detergent; lipopolysaccharide; glycosyltransferase; WaaG; fluorescence; circular dichroism; NMR; paramagnetic relaxation enhancement; model-free approach; dynamics; Biophysics; biofysik;

    Sammanfattning : Biological membranes form a protective barrier around cells and cellular compartments. A broad range of biochemical processes occur in or at membranes demonstrating that they are not only of structural but also of functional importance. One important class of membrane proteins are membrane-associated glycosyltransferases. LÄS MER

  5. 9. Biophysical studies of membrane associated biomolecular interactions

    Författare :Weihua Ye; Arnold Maliniak; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Membrane associated interactions play important roles in various biological processes. The aim of this thesis is to study two types of membrane associated interactions by using biophysical methods, particularly NMR. First, the interaction of a targeting peptide and a receptor attached to membrane has been studied. LÄS MER

  7. 10. Membrane interactions of glycosyltransferases

    Författare :Jobst Liebau; Lena Mäler; Christofer Lendel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipid; bicelle; glycosyltransferase; NMR; Biophysics; biofysik;

    Sammanfattning : Many important biological processes occur near or in membranes. The role of membranes is not merely confined to compartmentalization, they also form the matrix for membrane associated proteins and are of functional importance. Membrane associated proteins on the other hand require specific membrane properties for proper function. LÄS MER