Sökning: "bicelles"

Visar resultat 11 - 15 av 15 avhandlingar innehållade ordet bicelles.

  1. 11. Functional dynamics of glycosyltransferases : Solution-state NMR studies of peripheral membrane proteins involved in glycolipid biosynthesis in bacteria

    Författare :Joan Patrick; Lena Mäler; Magnus Wolf-Watz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Sammanfattning : Antibiotic resistance is an existential threat enabled by bacterial adaptation and fuelled by inappropriate use of medication. The ensuing shortage of effective treatments has led to a rise in deaths linked to resistant bacterial pathogens. LÄS MER

  3. 12. Biophysical studies of membrane interacting peptides derived from viral and Prion proteins

    Författare :Kamila Oglęcka; Astrid Gräslund; Stephen White; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Prion peptides; Doppel peptide; Influenza fusion peptides; peptide-membrane interactions; translocation; linear dichroism; circular dichroism; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : This thesis focuses on peptides derived from the Prion, Doppel and Influenza haemagglutinin proteins in the context of bilayer interactions with model membranes and live cells. The studies involve spectroscopic techniques like fluorescence, fluorescence correlation spectroscopy (FCS), circular and linear dichroism (CD and LD), confocal fluorescence microscopy and NMR. LÄS MER

  4. 13. Polarized light spectroscopy studies of model membranes and DNA

    Författare :Maxim Kogan; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; emission; ruthenium dipyridophenazine complex; lipid bilayer; linear dichroism; membrane model; membrane orientation; bimolecular probe; DNA;

    Sammanfattning : Over the past decades Linear Dichroism (LD) spectroscopy has proven to be a powerful tool for studies of structure and functioning of different cell constituents, including DNA, cell membranes and proteins. Due to structural complexity of cell constituents, the LD studies of biomolecules depend on development of simplified model systems, which can mimic the original structure and functionality of the cell components. LÄS MER

  5. 14. Computer Simulations of Membrane–Sugar Interactions

    Författare :Jon Kapla; Arnold Maliniak; Alexander Lyubartsev; Ilpo Vattulainen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular simulations; Molecular dynamics; Lipid bilayers; Carbohydrates; Biological membranes; Trehalose; Glycolipids; Membrane—sugar interactions; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : Carbohydrate molecules are essential parts of living cells. They are used as energy storage and signal substances, and they can be found incorporated in the cell membranes as attachments to glycoproteins and glycolipids, but also as free molecules. LÄS MER

  7. 15. Dynorphin A – Interactions with receptors and the membrane bilayer

    Författare :Johannes Björnerås; Lena Mäler; Astrid Gräslund; Göran Widmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik; Biochemistry; biokemi;

    Sammanfattning : The work presented in this thesis concerns the dynorphin neuropeptides, and dynorphin A (DynA) in particular. DynA belongs to the wider class of typical opioid peptides that, together with the opioid receptors, a four-membered family of GPCR membrane proteins, form the opioid system. LÄS MER