Sökning: "bhMSH2"

Hittade 1 avhandling innehållade ordet bhMSH2.

  1. 1. Molecular genetic studies on genes involved in hereditary nonpolyposis colorectal cancer (HNPCC)

    Författare :Tao Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :colorectal cancer; endometrial cancer; HNPCC; mismatch repair genes; bhMSH2; hMLH1; hPMS1; hPMS2; hMSH6; mutation screening; MSI; LOH.;

    Sammanfattning : Colorectal cancer (CRC) is a major public health problem in Western countries, and it is the third leading cause of death from cancer in both males and females. Inherited predisposition can be divided into two subgroups based on the absence or the presence of multiple benign colorectal polyps. LÄS MER