Sökning: "benzofuran"

Hittade 3 avhandlingar innehållade ordet benzofuran.

  1. 1. Studies of different secondary metabolites : Natural products from the mevalonate pathway

    Författare :Mariela Alejandra Gonzales Ramirez; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Natural products; fungi; Galiellalactone; Galiella rufa; Trichilia adolfi; benzofuran;

    Sammanfattning : Natural products, also called secondary metabolites, are small molecules that are not involved in main life processes. These can be produced by any living organism and play important roles as chemical weapons, protecting the organism from the competitive environment. LÄS MER

  3. 2. Towards novel antibacterials : Synthesis and identification of natural product inspired inhibitors of Chlamydia trachomatis and development of chemical probes targeting virulence of Pseudomonas aeruginosa

    Författare :Michael Saleeb; Mikael Elofsson; Anna Linusson Jonsson; Andreas Kirschning; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibacterials; antibiotics; small molecules; natural products; benzofuran; dihydrobenzofuran; the type III secretion system; Pseudomonas aeruginosa; Chlamydia trachomatis; phenotypic screening; high-throughput screening; surface plasmon resonance; drug discovery; bacterial toxins; enzyme inhibitors; organisk kemi; Organic Chemistry;

    Sammanfattning : Antibiotic resistance has evolved significantly to become one of the serious threats to public health today. Yet, the pipeline of new antibiotics is drying up and is lagging behind the challenging needs. LÄS MER

  4. 3. Palladium Catalysis in Directed C-H Bond Activation and Cycloisomerisation Reactions

    Författare :Michael Oschmann; Jan-Erling Bäckvall; Oscar Verho; Jose Luis Mascareñas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Palladium II ; Catalysis; C-H Functionalisation; Transamidation; XAS; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis concerns the development of Pd(II)-catalysed synthetic methodologies for the preparation of biologically active compounds.In the first part (paper I-III), unactivated C–H bonds of a cyclobutane derivative are selectively functionalised using a directing group starting from the feedstock compound verbenone (paper I). LÄS MER