Sökning: "bedside"

Visar resultat 1 - 5 av 79 avhandlingar innehållade ordet bedside.

  1. 1. CD19-targeting CAR T Cells for Treatment of B Cell Malignancies : From Bench to Bedside

    Författare :Hannah Karlsson; Angelica Loskog; Karl-Johan Malmberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chimeric antigen receptors; CAR T cells; T cell therapy; immunotherapy; CD19; Bcl-2 family inhibitors; B cell malignancies; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Immunotherapy for cancer is a young research field progressing at high speed. The first chimera of an antibody and a signaling chain was designed by Zelig Eshhar and was later further developed to enhance existing T cell therapy by combining a single-chain fragment of an antibody with the CD3 zeta chain of the TCR complex. LÄS MER

  3. 2. Aerococcal infections - from bedside to bench and back

    Författare :Erik Senneby; Infektionsmedicin; []
    Nyckelord :Aerococcal infections;

    Sammanfattning : The genus Aerococcus comprises eight species of Gram-positive cocci. The incidence and the clinical importance of aerococcal infections have been underestimated in the past, due to species identification difficulties. LÄS MER

  4. 3. Promoting healing of skin and mucosa by immunomodulation using CXCL12 producing lactic acid bacteria : From bench to bedside

    Författare :Emelie Öhnstedt; Mia Phillipson; Neil Forbes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L.reuteri; wound healing; non-healing wounds; ILP100; colitis; immunotherapy;

    Sammanfattning : Immunotherapies direct the immune system to respond in a certain way, such as to fight cancer or to dampen inflammation. In this thesis, a new immunotherapy, ILP100, is developed using a technology that allows for local production of short-lived immunoregulatory proteins that previously have been undruggable. LÄS MER

  5. 4. Detection of Myocardial Ischemia using Real-Time Myocardial Contrast Echocardiography

    Författare :Petri Gudmundsson; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardial contrast echocardiography; MCE; stress echocardiography; adenosine; perfusion; real-time; visual; quantative; wall motion; power modulation; bedside; SPECT; coronary insufficiency;

    Sammanfattning : Diagnostisering av syrebrist i hjärtmuskeln med hjälp av kontrastförstärkt ultraljudsundersökning av hjärtmuskelns genomblödning. Ultraljudsundersökning av hjärtat (ekokardiografi) används mycket inom hjärtsjukvården idag, oftast för att utreda hjärtats och hjärtklaffarnas anatomi och funktion. LÄS MER

  7. 5. [68Ga]Exendin-4: Bench-to-Bedside : PET molecular imaging of the GLP-1 receptor for diabetes and cancer

    Författare :Ram kumar Selvaraju; Olof Eriksson; Olle Korsgren; Lars Johansson; Martin Gotthardt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; [68Ga]Exendin-4; beta cell imaging; insulinoma; dosimetry;

    Sammanfattning : Diabetes epidemic is underway. Beta cell dysfunction (BCF) and loss of beta cell mass (BCM) are known to be key events in its progression. Currently, there are no reliable techniques to estimate or follow the loss of BCM, in vivo. LÄS MER