Sökning: "basis"

Visar resultat 11 - 15 av 5055 avhandlingar innehållade ordet basis.

  1. 11. Basis for reclassification of nasopharyngeal carcinoma

    Författare :Jian-Yong Shao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nasopharyngeal carcinoma (NPC) shows broad differences in racial and geographical distribution, radiosensitivity, and a multifactorial etiology. This thesis aims to identify molecular biomarkers with potentially valuable for prognostic implications in NPC. LÄS MER

  2. 12. Molecular basis of estrogen receptor antagonism

    Författare :Nina Heldring; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Estrogen Receptor; antagonism; receptor signaling; phytoestrogen and conformational changes;

    Sammanfattning : Estrogen Receptors (ERs), ERα and ERβ, are responsible for mediating the physiological effects of the steroid hormone 17b-estradiol and structurally related compounds. ER signaling is a complex process where the combined effects of accessory proteins, known as coregulators, promoter characteristics and influence from other signaling systems, determine the cell-specific transcriptional response in a given situation. LÄS MER

  3. 13. On a Need to Know Basis : A Conceptual and Methodological Framework for Modelling and Analysis of Information Demand in an Enterprise Context

    Författare :Magnus Jandinger; Kurt Sandkuhl; Ulf Seigerroth; Sture Hägglund; Eva Söderström; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : While the amount of information, readily available to workers in information- and knowledge intensive business- and industrial contexts, only seem to increase with every day, those workers continue to have difficulties in finding and managing relevant and needed information despite the numerous technical, organisational, and practical approaches promising a remedy to the situation. In this dissertation it is claimed that the main reason for the shortcomings of such approaches are a lack of understanding of the underlying information demand people and organisations have in relation to performing work tasks. LÄS MER

  4. 14. Oversampled radial basis function methods for solving partial differential equations

    Författare :Igor Tominec; Elisabeth Larsson; Bengt Fornberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radial basis function; PDE; oversampling; stability; RBF-FD; RBF-PUM; unfitted;

    Sammanfattning : Partial differential equations (PDEs) describe complex real-world phenomena such as weather dynamics,  object deformations, financial trading prices, and fluid-structure interaction.  The solutions of PDEs are commonly used to enhance the understanding of these phenomena and also as leverage to make technological improvements to consumer products. LÄS MER

  5. 15. High Order Local Radial Basis Function Methods for Atmospheric Flow Simulations

    Författare :Erik Lehto; Elisabeth Larsson; Natasha Flyer; Tobin Driscoll; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radial basis function; meshless method; high order finite difference; atmospheric flow; hyper-viscosity; stable algorithm; Scientific Computing; Beräkningsvetenskap;

    Sammanfattning : Since the introduction of modern computers, numerical methods for atmospheric simulations have routinely been applied for weather prediction, and in the last fifty years, there has been a steady improvement in the accuracy of forecasts. Accurate numerical models of the atmosphere are also becoming more important as researchers rely on global climate simulations to assess and understand the impact of global warming. LÄS MER