Sökning: "basal"
Visar resultat 6 - 10 av 914 avhandlingar innehållade ordet basal.
6. Effects of antipsychotics on GABA neurons in the basal ganglia of the rat
Sammanfattning : Antipsychotics are used in the treatment of psychosis and, based on their propensities to induce extrapyramidal side effects (EPS), are divided into typical (haloperidol) and atypical (clozapine) subtypes. The incidence of EPS, arises from an imbalance in the neurotransmission between two majorGABAergic pathways of the basal ganglia that connect the striatum directly to the entopeduncular nucleus (EP) and the substantia nigra reticulata or indirectly via the globus pallidus and the subthalamic nucleus. LÄS MER
7. Anatomical, neurochemical and behavioural consequences of immunotoxin lesions of the basal forebrain cholinergic system
Sammanfattning : The cholinergic hypothesis of geriatric memory dysfunction suggests that the learning and memory deficits representing the cardinal symptoms of dementia in the aged and in patients suffering from Alzheimer's disease may be attributable to a decline in the function of the cholinergic projection systems of the basal forebrain. Although many studies have addressed the issue of a causal relationship between cholinergic hypofunction and cognitive disturbance, analyses of the functional role of the basal forebrain cholinergic neuronal systems in the brain have so far been hampered by the lack of an efficient and specific cholinergic neurotoxin. LÄS MER
8. Basal boundary conditions, stability and verification in glaciological numerical models
Sammanfattning : To increase our understanding of how ice sheets and glaciers interact with the climate system, numerical models have become an indispensable tool. However, the complexity of these systems and the natural limitation in computational power is reflected in the simplifications of the represented processes and the spatial and temporal resolution of the models. LÄS MER
9. The proprioception and neuromuscular stability of the basal thumb joint
Sammanfattning : OBJECTIVES: The basal thumb joint, or the first carpometacarpal joint (CMC1) is an enigmatic construction. The concavo-convex shape of the CMC1 and wide range of movement, allows for both precision and power grips and is particularly susceptible to the development of osteoarthritis. LÄS MER
10. Computational Dissection of the Basal Ganglia : functions and dynamics in health and disease
Sammanfattning : The basal ganglia (BG), a group of nuclei in the forebrain of all vertebrates, are important for behavioral selection. BG receive contextual input from most cortical areas as well as from parts of the thalamus, and provide output to brain systems that are involved in the generation of behavior, i.e. the thalamus and the brain stem. LÄS MER