Sökning: "basal ganglia"

Visar resultat 16 - 20 av 99 avhandlingar innehållade orden basal ganglia.

  1. 16. Dissecting the intrastriatal neuronal circuitry that regulates direct and indirect striatal projections

    Författare :Henrike Planert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :basal ganglia;

    Sammanfattning : The basal ganglia (BG) are a group of subcortical nuclei that are interconnected in multiple parallel cortico-BG-thalamocortical loops. They have been implicated in many functions, among them action control and motor learning. The striatum forms the main input nucleus of the BG. LÄS MER

  3. 17. The Role of the Cortico-Basal Ganglia-System in Voluntary Movements

    Författare :Martin Tamté; Integrativ neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurophysiology; Electrophysiology; Pharmacology; Motor Systems; Voluntary movements; Philosophy; In vivo; Corticostriatal; Parkinson s disease; Dyskinesia; Levodopa; Multiple Electrode Arrays;

    Sammanfattning : Bodies with multiple limbs and joints have endless possibilities to move around in their surrounding space. How the nervous system controls this amount of degrees of freedom in motor execution is a question under vigorous debate. LÄS MER

  4. 18. United in Diversity : A Physiological and Molecular Characterization of Subpopulations in the Basal Ganglia Circuitry

    Författare :Thomas Viereckel; Åsa Wallén-Mackenzie; Åsa Konradsson-Geuken; Erika Comasco; Per Svenningsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Glutamate; Optogenetics; Amperometry; Histology; Midbrain; Subthalamic Nucleus; Parkinson s disease; Ventral Tegmental Area; Substantia Nigra; Co-release;

    Sammanfattning : The Basal Ganglia consist of a number of different nuclei that form a diverse circuitry of GABAergic, dopaminergic and glutamatergic neurons. This complex network is further organized in subcircuits that govern limbic and motor functions in humans and other vertebrates. LÄS MER

  5. 19. Physiopathological aspects of NMDA transmission in the basal ganglia : in vitro and in vivo release studies

    Författare :Michele Morari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :basal ganglia; NMDA; dizocilpine; microdialysis; slices; synaptosomes; dopamine; acetylcholine; glutamate; GABA; 6OH-dopamine;

    Sammanfattning : N-methyl-D-aspartic acid (NMDA) is an excitatory amino acid selectively acting on a subclass of glutamate receptors (the NMDA ionotropic receptor) which has been involved in many of the physiological and pathological effects of glutamate in the CNS. The basal ganglia are particularly enriched in NMDA receptors and NMDA receptor activation in the basal ganglia has been involved in the expression of motor behaviour. LÄS MER

  7. 20. Interaction of sensory and motor signals in the basal ganglia in health and disease

    Författare :Mohammadreza Mohagheghi Nejad; Jeanette Hellgren Kotaleski; Robert Schmidt; Arthur Leblois; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Computer Science; Datalogi;

    Sammanfattning : The basal ganglia, a set of deep forebrain nuclei, are among the brain regions involved in movement initiation and suppression. Although many studies have investigated the neural coding underlying these two aspects of movement, there are still questions that need to be addressed. LÄS MER