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1. 1. Structural and Interaction Studies of Bacterial Polysaccharides by NMR Spectroscopy

   Författare :Eva-Lisa Nordmark; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial polysaccharides; NMR; interaction studies; structural studies; Escherichia coli; Salmonella enteritidis; Streptococcus thermophilus; Propionibacterium freudenreichii; Pseudoalteromonas aliena; P22 TSP; Organic chemistry; Organisk kemi;

   Sammanfattning : An introduction to bacterial polysaccharides and the methods for structural determination are described in the first two parts of the thesis.In a structural elucidation of bacterial polysaccharides NMR experiments are important as is component analysis. A short description of immunochemical methods such as enzyme immunoassays is included. LÄS MER

3. 2. Structural and conformational studies of bacterial polysaccharides employing NMR spectroscopy

   Författare :Mikael Staaf; Jesus Jiminez-Barbero; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacterial polysaccharides; Magnetic resonance spectroscopy; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

   Sammanfattning : Methods and approaches for performing structural and conformational analysis of bacterial polysaccharides in solution are described. The structure of one exopolysaccharide from Lactobacillus helveticus and two O-antigens from Escherichia coli have been determined using NMR spectroscopy, chemical degradation and mass spectrometry. LÄS MER

4. 3. Structural studies on some bacterial polysaccharides

   Författare :Jörgen Lönngren; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER

5. 4. Biosynthesis of bacterial polysaccharides by novel glycosyltransferase enzymes

   Författare :Shu-Chieh Chang; Yves S. Y. Hsieh; Ute Römling; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; Bioteknologi;

   Sammanfattning : Within the intricate microbiological realm, exopolysaccharides (EPS) emerge as a significant class of high molecular weight polysaccharides, serving pivotal roles in bacterial survival, virulence, communication, and defense against environmental adversities. The versatile nature of bacterial EPS extends beyond mere biological functions, reaching into medications, cosmetics, functional food, and sustainable industries. LÄS MER

7. 5. Synthesis and analysis of carbohydrates related to bacterial polysaccharides

   Författare :Hani Mobarak; Göran Widmalm; Ulf Nilsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; synthesis; conformation; NMR; O-antigen; computer-assisted structure elucidation; Organic Chemistry; organisk kemi;

   Sammanfattning : The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacteria to survive and communicate with the host biological system. The thesis discusses different properties of carbohydrates that are essential for understanding the bacterial behavior in biological systems. LÄS MER