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Visar resultat 1 - 5 av 20 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Bacteriological aspects of treatment failures in streptococcal tonsillitis

    Författare :Eva Grahn; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ß-streptococci; treatment failure; a-streptococci; bacterial interference; beta-lactamase; Phenoxymethylpenicillin; penicillin tolerance;

    Sammanfattning : ß-hemolytic streptococci persist in 10-25% of patients with acute streptococal tonsillitis (about 10.000-25.000 per year in Sweden) in spite of treatment with a recommended dosage and schedule of Phenoxymethylpenicillin. LÄS MER

  3. 2. Effect of Probiotics on Caries-related Variables

    Författare :Sahal Alforaidi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial interference; ; Caries; Caries prevention; ; Dental biofilm; ; Dental plaque; ; Lactobacilli; Lactobacillus reuteri; ; Streptococcus mutans; ; Plaque acidogenicity; ; Probiotics; qPCR; Saliva; Virulence;

    Sammanfattning : In relation to the caries disease, the aims of this thesis were to investigate the effect of probiotic drops on different caries-related variables in vivo (Papers I & III), on interference capability and genetic response to different metabolites in vitro (II) and systematically to review the best mode and dose of administration based on the examined oral outcomes (IV). The effects on colonisation and cariogenic bacteria were studied in plaque and saliva via plating and qPCR-analyses in teenagers and orthodontic patients after short-term exposure. LÄS MER

  4. 3. The efficacy of bacterial viruses against multi-resistant Escherichia coli: from isolation to pharmacology

    Författare :Mohammadali Khan Mirzaei; Anders Nilsson; Rob Lavigne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phage therapy; Multiresistant E. coli; Pharmacodynamics; Pharmacokinetics; Bacterial viruses; Genomic; proteomic; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The increase of multi-resistant bacteria highlights that the golden era of antibiotics is ending and that alternative treatmentsare urgently needed. Phages have been historically used to treat bacterial infections prior to the discovery of antibiotics and have gained renewed interest in the past decade. LÄS MER

  5. 4. Functional Studies of Some Immune Relevant Genes in a Crustacean

    Författare :Haipeng Liu; Kenneth Söderhäll; Irene Söderhäll; Lage Cerenius; Ingrid Faye; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; anti-LPS factor; crayfish; hemocyte; innate immunity; melanization; phenoloxidase; RNA interference; WSSV; Biology; Biologi;

    Sammanfattning : The freshwater crayfish, Pacifastacus leniusculus, mounts a strong innate immune response against microbes such as viruses and bacteria. In this thesis, a novel RNA interference (RNAi) method mediated with histone H2A was developed and applied in crayfish hematopoietic tissue cell cultures for gene functional studies. LÄS MER

  7. 5. Pharmaceutical and mutational interference with virulence of Salmonella enterica serovar typhimurium

    Författare :Aurel Negrea; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Within the species Salmonella enterica are a diverse range of bacteria that can cause illness in humans and many animals. Salmonellae are extremely versatile and can adapt to a variety of environments and hosts. Typhoid and paratyphoid fever, caused by human-restricted S. enterica serovars Typhi and Paratyphi are common in the developing world. LÄS MER