Sökning: "bacterial adaptation"

Visar resultat 16 - 20 av 72 avhandlingar innehållade orden bacterial adaptation.

  1. 16. Mechanisms of Adaptation to Deformylase Inhibitors

    Författare :Anna Zorzet; Dan Andersson; Paul Rainey; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotic resistance; compensatory evolution; compensatory mutations; protein synthesis; initiation factor 2; initiator tRNA; formylation; peptide deformylase inhibitors; Bacteriology; Bakteriologi; Mikrobiologi; Microbiology; Biokemi; Biochemistry; Geography; Geografi;

    Sammanfattning : Antibiotic resistance is a growing problem on a global scale. Increasing numbers of bacteria resistant toward one or multiple antibiotics could return us to the high mortality rates for infectious diseases of the pre-antibiotic era. LÄS MER

  3. 17. Helicobacter pylori adhesion and patho-adaptation : the role of BabA and SabA adhesins in persistent infection and chronic inflammation

    Författare :Jafar Mahdavi; Henrik Clausen; Umeå universitet; []
    Nyckelord :H. pylori; BabA; adhesin; Lewis b; MUC5AC; sialyl-dimeric-Lewis x; chronic inflammation; SabA; Lewis x; LPS; odontologi; Odontology;

    Sammanfattning : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. LÄS MER

  4. 18. Genetic adaptation of salmonella enterica to phagocytic cells

    Författare :Sofia Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Salmonella; macrophages; host-adaptation; microarray; nitric oxide;

    Sammanfattning : Salmonella enterica is a collection of closely related enteric bacteria that as a species is capable of infecting a wide variety of hosts. S. enterica serovar Typhimurium, (S. Typhimurium), causes a systemic disease in mice which in many aspects resembles human typhoid fever caused by S. LÄS MER

  5. 19. Mechanisms of genetic adaptation in Helicobacter pylori

    Författare :Anna Skoglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Helicobacter pylori is one of the most common bacteria worldwide, estimated to infect half of the human population. The infection is usually established in childhood and persists for a lifetime, unless treated. Most individuals never experience symptoms from H. LÄS MER

  7. 20. Exploring the Interplay of Lipids and Membrane Proteins

    Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

    Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER