Sökning: "bacterial DNA"

Visar resultat 1 - 5 av 293 avhandlingar innehållade orden bacterial DNA.

  1. 1. Stability of bacterial DNA in relation to microbial detection in teeth

    Författare :Malin Brundin; Ulf Sjögren; Anders Johansson; David Figdor; Inge Fristad; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell-bound DNA; cell-death; dentine; DNA binding affinity; DNA decomposition; DNA preservation; extracellular DNA; hydroxyapatite; PCR; polymerase chain reaction; odontologi; Odontology;

    Sammanfattning : The fate of DNA from dead cells is an important issue when interpreting results from root canal infections analysed by the PCR technique. DNA from dead bacterial cells is known to be detectable long time after cell death and its stability is dependent on many different factors. LÄS MER

  3. 2. Bacterial DNA repair and molecular search

    Författare :Arvid H. Gynnå; Johan Elf; Stephen Kowalczykowski; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA repair; DNA damage; homologous recombination; homologous repair; recombination; RecA; I-SceI; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Surveillance and repair of DNA damage is necessary in all kinds of life. Different types of DNA damage require different repair mechanisms, but these mechanisms are often similar in all domains of life. The most serious type of damage, double stranded DNA breaks, are for example repaired in conceptually similar ways in both bacteria and eukaryotes. LÄS MER

  4. 3. Single DNA Molecule Analysis – New Tools for Medical Diagnosis

    Författare :My Nyblom; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; optical DNA mapping; DNA damage; DNA; single-molecule analysis; fluorescence microscopy; antibiotic resistance; nanofluidics; genetics;

    Sammanfattning : The DNA molecule, the blueprint of life, contains an enormous amount of information. The information is coded by the combination of four bases; adenine, cytosine, guanine, and thymine, that, together with the sugar-phosphate backbones, make up the DNA double helix. LÄS MER

  5. 4. DNA vaccines and bacterial DNA in immunity

    Författare :Lisa Charlotta Bandholtz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA vaccine; CpG DNA; antimicrobial peptides C. pneumoniae; Shigella spp;

    Sammanfattning : This thesis describes DNA-based vaccination and the importance of bacterial DNA in different immunological perspectives. Intranasal (i.n.) DNA vaccination utilizing a plasmid encoding the chlamydial heat shock protein 60 (p-hsp-60) generated lower bacterial burden and reduced pathology in the lungs of mice after subsequent infection with C. LÄS MER

  7. 5. Dynamics of the Bacterial Genome : Rates and Mechanisms of Mutation

    Författare :Sanna Koskiniemi; Dan Andersson; Diarmaid Hughes; Ivan Matic; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; Microbiology; Mikrobiologi; Bacteriology; Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Sammanfattning : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. LÄS MER