Sökning: "b-catenin"

Visar resultat 11 - 13 av 13 avhandlingar innehållade ordet b-catenin.

  1. 11. Mechanisms of inflammatory signalling in chronic lung diseases : transcriptomics & metabolomics approaches

    Författare :Bettina Levänen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Sarcoidosis, asthma and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases with many different clinical phenotypes. A central characteristic of all three diseases is the altered airway function due to inflammation. LÄS MER

  2. 12. Molecular subclassification, stem cell markers and growth regulatory pathways in gliomas

    Författare :Karl Holmberg Olausson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Glioblastoma is the most common and aggressive primary brain tumor in adults. Median survival is no more than 15 months, even with combined treatment regimens. The lack of accurate pre-clinical model systems has limited the development of new treatment options for this deadly disease. LÄS MER

  3. 13. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

    Författare :Marzieh Jönsson; Bröstca-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; signalling; breast cancer; Wnt-5a; mammary epithelial cells; cancer; onkologi; Cytologi; cancerology;

    Sammanfattning : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. LÄS MER