Sökning: "azurocidin"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet azurocidin.

1. 1. Function of granulocytes after burns and trauma, associations with pulmonary vascular permeability, acute respiratory distress syndrome, and immunomodulation

   Författare :Joakim Johansson; Folke Sjöberg; Lennart Lindbom; Sven-Erik Ricksten; Linköpings universitet; []
   Nyckelord :ARDS; azurocidin; burn; CAP-37; critical care; granulocyte; HBP; histamine; intensive care; leucocyte; leukocyte; mediator; methylhistamine; MOF; oedema; neutrophil; permeability; PMN; trauma; vascular permeability;

   Sammanfattning : Background: Our innate immunesystem protects us from infections but, since its methods is not all specific for microorganisms, may also induce collateral damage.Severe physical injury often proved deadly throughout evolution. Such injuries may induce massive collateral damage. LÄS MER

3. 2. Biosynthesis, Processing, and Sorting of Human Neutrophil Granule Proteins. Focus on Cathepsin G, Proteinase 3, and Azurocidin

   Författare :Daniel Garwicz; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; differentiation; bone marrow progenitor cells; preproform; mutations; Cell lines; transfection; extracellulära vätskor;

   Sammanfattning : The neutrophil granulocyte contains a number of multifunctional proteins stored in different subsets of granules. The azurophil granules, synthesized early during differentiation, harbour leukocyte elastase, cathepsin G, proteinase 3, and azurocidin; the members of the serprocidin family. LÄS MER

4. 3. On the Biosynthesis and Processing of Cathepsin G, Leukocyte Elastase, and Azurocidin ­ neutrophil granule members of a hematopoietic serine protease superfamily

   Författare :Anders Lindmark; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; sorting; Activation; propeptide; Hematologi; extracellulära vätskor;

   Sammanfattning : The serine proteases cathepsin G, leukocyte elastase, proteinase 3, and the inactive protease homologue azurocidin, stored in the azurophil granules of neutrophils, belong to a hematopoietic serine protease superfamily with members in mature effector cells of bone marrow origin. Promonocytic U-937 cells were used for studying the biosynthesis of cathepsin G and leukocyte elastase by biosynthetic radiolabelling. LÄS MER

5. 4. Novel insulin-like growth factor-binding protein proteases : detection and characterization

   Författare :Jing Wang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :IGFs; IGFBP-1. IGFBP-3; azurocidin HBP CAP37; IGFBP protease; gender;

   Sammanfattning : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. LÄS MER

7. 5. Proteolysis of insulin-like growth factor-binding protein-1, -2 and -4 : function of fragments

   Författare :Katrin Brandt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Insulin-like growth factor;

   Sammanfattning : The insulin-like growth factors (IGF-I and IGF-II) stimulate cell growth, survival and differentiation, and have insulin-like activity. A family of six IGF-binding proteins (IGFBP-1 through -6) bind to IGFs with high affinity and modulate their activity in the circulation and locally at cell-surface receptors. LÄS MER