Sökning: "aziridines"

Visar resultat 11 - 15 av 21 avhandlingar innehållade ordet aziridines.

  1. 11. Radical Cyclization Approaches to Pyrrolidines

    Författare :Magnus Beşev; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Radical cyclization; diastereselectivity; pyrrolidine; pyrroline; thiazoline; aziridine; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. LÄS MER

  3. 12. Asymmetric transfer hydrogenation of aromatic ketones and azirines with NH-ligands

    Författare :Peter Roth; Krister Zetterberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : The Ru(arene)[(1S, 3R, 4R)-3-(Hydroxymethyl)-2-azabicyclo[2.2.1]heptane catalyst was optimized as ligand in the asymmetric transfer hydrogenation of ketones and resulted in increased activity and enantioselectivity of the catalyst. LÄS MER

  4. 13. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization

    Författare :Stefan Berlin; Lars Engman; Mario D. Bachi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; radical; cyclization; carbonylation; melatonin; pyrrolidine; pyrrolidin-3-one; tetrahydrofuran-3-one; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. LÄS MER

  5. 14. Synthesis of Tetrahydrofuran and Pyrrolidine Derivatives Utilising Radical Reactions : Organochalcogenides in Reductive, Carbonylative and Group-Transfer Cyclisation

    Författare :Cecilia Ericsson; Lars Engman; Ilhyong Ryu; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes free-radical reactions for the construction of tetrahydrofuran and pyrrolidine derivatives. The studies are concerned with (i) diastereoselectivity in radical cyclisation, (ii) construction of tetrahydrofuran-3-ones and pyrrolidin-3-ones via radical carbonylation/cyclisation and (iii) synthesis of tetrahydrofuran derivatives via group-transfer cyclisation of organochalcogen compounds. LÄS MER

  7. 15. Fine-tuning of the catalytic activity and selectivity of palladium pincer complexes

    Författare :Juhanes Aydin; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : This thesis is focused on optimization of the catalytic properties of so-called pincer complexes. This work involved synthesis of a large variety of palladium pincer complexes, which were applied in various organic transformations. LÄS MER