Sökning: "axonal growth"

Visar resultat 11 - 15 av 62 avhandlingar innehållade orden axonal growth.

  1. 11. Dissection of immunity controlling spread and growth of Listeria monocytogenes in neuronal cells

    Författare :Yuxuan Jin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :L. monocytogenes; nervous system; neuroinvasion; IFN-ã; CSF-1; neuron; NK cells; T cells; MHC;

    Sammanfattning : Listeria monocytogenes is a Grain-positive, facultative intracellular bacterium that causes severe infections in the nervous system of domestic animals and humans. Rhombencephalitis (brainstem encephalitis) due to L. monocytogenes, is a localized brainstem infection that is frequent in ruminants, and has been reported in humans as well. LÄS MER

  3. 12. On optic nerve injury : experimental studies on axonal regeneration in the adult mammalian CNS

    Författare :Marcus Ohlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Astroglia; axon; degeneration; glial scar; immunohistochemistry; macrophage; methylprednisolone; microglia; neurosurgery; optic nerve; rat; regeneration and visual evoked potentials;

    Sammanfattning : Optic nerve injury may occur after a trauma to the head and in many cases it causes partial or total blindness. Today, these patients cannot be offered any specific treatment to restore visual function. LÄS MER

  4. 13. Markers and mechanisms of abnormal neurovascular development in the preterm infant

    Författare :William Hellström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neonatology; Brain development; Extremely preterm infant; Brain volume; Retinopathy of prematurity; Insulin-like growth factor 1; Neurofilament light; Neurodevelopment;

    Sammanfattning : Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes are sparse. LÄS MER

  5. 14. On traumatic lesion to the spinal cord and dorsal spinal roots : factors influencing axonal regrowth across the border between the central and peripheral nervous system in the rat and man

    Författare :Tomas Lindholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunohistochemistry; in situ hybridization; rat; man; axotomy; regeneration; motoneuron; ; CNS; PNS; tenascin; macrophages; BBB; scar; neuregulin; ErbB3 4; semaphorin; neuropilin; VEGF; olfactory system; DRG; DRT; SNT; SNC.;

    Sammanfattning : Nerve cells are depending on their environment. Glial cells, astrocytes and oligodendrocytes in the central nervous system (CNS) make up a totally different milieu and characteristics than the distinguishing qualities of the peripheral nervous system (PNS), where the nerve cells are surrounded by Schwann cells. LÄS MER

  7. 15. Transcriptional regulation of the neuropeptide galanin : special reference to axotomy

    Författare :Jacqueline D Corness; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :galanin; axotomy; nerve injury; neuropeptide; leukaemia inhibiting factor; transcription; dorsal root ganglion; nerve growth factor;

    Sammanfattning : Galanin is a neuropeptide which is located in both the central and peripheral nervous system. In peripheral neurones, this peptide is thought to be involved in influencing pain sensation after nerve injury (neuropathic pain) and also in the regeneration of peripheral nerves. LÄS MER