Sökning: "avidity"
Visar resultat 11 - 15 av 41 avhandlingar innehållade ordet avidity.
11. Leukocyte responses to pathogens : integrins, membrane rafts and nitric oxide
Sammanfattning : During microbial invasion, leukocytes of the innate immunity are rapidly recruited to the site of infection where they internalize (phagocytose), kill and digest the invaders. To aid this process, leukocytes express surface receptors such as Toll-like receptors, β2-integrins and Fc-receptors. LÄS MER
12. Immunization approaches and molecular signatures for mucosal immunity to primary and recurrent genital herpes
Sammanfattning : Genital herpes is most commonly caused by herpes simplex virus type 2 (HSV-2), and is a prevalent sexually transmitted infection worldwide. Despite numerous efforts, there is currently no licensed vaccine against the disease. LÄS MER
13. Development and evaluation of new therapeutic interventions for chronic hepatitis C virus infection
Sammanfattning : The hepatitis C virus (HCV) is a major global health problem with around 130-150 million individuals chronically infected and it is estimated that 2 millions are newly infected each year. The HCV infection is one of the major causes of liver disease and the infection is characterized by a slow and silent progression. LÄS MER
14. CD8alpha/alpha+ T-cells and immune memory
Sammanfattning : A better understanding of T-cell memory formation is crucial for rationale vaccine design and the identification of correlates of immune protection. The CD8αα homodimer expressed on CD8+ T-cells is not anymore considered to represent a TCR co-receptor, it may rather represent a mechanism to modulate T-cell avidity and identify a subset of memory T-cells. LÄS MER
15. Humoral and cellular immune responses to proteins encoded by the hepatitis C virus
Sammanfattning : The hepatitis C virus (HCV) was the first described human pathogen of the hepaciviruses, a new genus within the flaviviridae family. A characteristic feature of HCV is that it has a high genetic heterogenecity. It is believed that the immune response is of vital importance to prevent, control, and to eradicate HCV infections. LÄS MER