Sökning: "autoinhibition"

Hittade 3 avhandlingar innehållade ordet autoinhibition.

  1. 1. Structural and dynamical basis of NusA´s role in transcription-coupled DNA repair

    Författare :Damasus Okeke; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Resonance assignment; DNA repair; transcription-repair coupling factors; transcription-coupled repair; NusA; DinB; UvrD; autoinhibition; DNA substrate; dynamics.;

    Sammanfattning : DNA repair processes involves a host of repair machineries that are able to recognize and repair the damaged DNA. Nucleotide excision repair (NER) pathway is one of these processes exploited by cells to remove bulky DNA lesions. LÄS MER

  3. 2. Allosteric control of ALC1-catalyzed nucleosome remodeling

    Författare :Laura C. Lehmann; Sebastian Deindl; Stefan D. Knight; Felix Müller-Planitz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ALC1; CHD1L; ATP-dependent chromatin remodeling; nucleosome; allosteric regulation; autoinhibition; macro domain; PARP; ADP-ribosylation; DNA damage; acidic patch; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : The genetic information of eukaryotic cells is packaged inside the nucleus as chromatin. This packaging restricts access to the DNA and therefore represents a barrier for processes such as DNA replication, repair, and gene expression. LÄS MER

  4. 3. Molecular mechanisms controlling dynamin recruitment to sites of endocytosis by SH3-domain containing proteins

    Författare :Anna Sundborger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endocytosis is a general cellular mechanism, which regulates a number of important events, including recycling of synaptic vesicles. Clathrin-mediated endocytosis is the best-characterized endocytic pathway in the cell. This internalization process involves the coat protein clathrin, the adaptor protein AP2 and a number of accessory proteins. LÄS MER