Sökning: "autoimmunity"
Visar resultat 16 - 20 av 416 avhandlingar innehållade ordet autoimmunity.
16. Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defence
Sammanfattning : The C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. LÄS MER
17. Biomarker Discovery in Cancer and Autoimmunity using an Affinity Proteomics Platform - a Tool for Personalized Medicine
Sammanfattning : Identification of novel biomarkers for early diagnosis, prognosis, and treatment decision will be instrumental for improving disease outcome for patients suffering from complex diseases, such as cancer and autoimmune disorders. Within personalized medicine, the use of circulating biomarkers will allow clinicians to tailor medical treatment based on individual characteristics of each patient, using minimally invasive sampling. LÄS MER
18. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis
Sammanfattning : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms. However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. LÄS MER
19. Polyglandular Autoimmune (PGA) Syndromes and associations to sarcoidosis
Sammanfattning : Polyglandular Autoimmune (PGA) syndrome type II in idiopathic Addison's disease: In a retrospective study of idiopathic Ad-dison's disease (median age at diagnosis 32.5 years, range 8-62; median observation time 17 years, range 0.5-41), 50% met the criteria for PGA syndrome type II. In PGA syndrome type II, 73% had ATD and 41% had IDDM. LÄS MER
20. Molecular Targets in Autoimmune Polyendocrine Syndrome Type1 and Their Clinical Implications
Sammanfattning : Autoimmune diseases occur when the immune system attacks and destroys healthy body tissue. Autoimmunity is known to cause a wide range of disorders, and is suspected to be responsible for many more. Most autoimmune disorders are chronic and cause severe morbidity for the patients, and are also costly for society. LÄS MER