Sökning: "autoimmune disorders"

Visar resultat 6 - 10 av 125 avhandlingar innehållade orden autoimmune disorders.

  1. 6. Pituitary autoantibodies in endocrine disorders

    Författare :Sophie Bensing; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Lymphocytic hypophysitis; hypopituitarism; empty sella syndrome; APS 1; autoantibodies; autoantigen; Secretogranin II; TDRD6.;

    Sammanfattning : Autoimmune endocrine disorders are characterised by the development of autoantibodies to specific autoantigens in the target organs. Lymphocytic hypophysitis (LyH) is a disease characterised by inflammation of the pituitary gland, often resulting in hypopituitarism. The aetiology of LyH is considered to be autoimmune. LÄS MER

  3. 7. Genetic factors predisposing to myasthenia gravis and related autoimmune disorders

    Författare :Ryan Ramanujam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myasthenia gravis (MG) is an autoimmune disorder in which patients experience weakness of the skeletal or ocular-bulbar muscles. In most patients, anti-AChR antibodies affect the signal across the neuromuscular junction necessary for muscular contraction. LÄS MER

  4. 8. Collagenous colitis. Epidemiology, risk factors, clinical presentation and associated autoimmune disorders

    Författare :Lina Vigren; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; collagenous colitis; epidemiology; inflammatory bowel disease; lymphocytic colitis; microscopic colitis; smoking;

    Sammanfattning : Collagenous colitis (CC) affects middle-aged women and results in chronic watery non-bloody diarrhoea. The incidence of CC has increased but has never been determined in southern Sweden. During the period 2001-2010 the mean annual incidence was stable; 5.4/105 (median age 71 years). LÄS MER

  5. 9. Co-stimulatory molecules : genes to protein in autoimmune and inflammatory disorders

    Författare :Priya Sakthivel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Co‐stimulatory molecules are antigen‐independent generators of secondary signals which aid in maintaining the homeostasis of the immune system. The most extensively studied co‐stimulatory pathway is CD28/CTLA‐4, expressed on the T cells, interacting with CD80/CD86, expressed on the antigen presenting cells (APC). LÄS MER

  7. 10. B cell regulation in autoimmune disease

    Författare :Shan Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our immune system protects us from both foreign antigens and self-derived autoantigens by sophisticated regulation. During an immune response, the innate and adaptive parts of the immune system closely collaborate at every stage of the response. LÄS MER